Research and Development Department, MiZ Company Limited, Kanagawa, Japan.
MiZ Inc., Newark, CA, USA.
Med Gas Res. 2024 Sep 1;14(3):89-95. doi: 10.4103/2045-9912.385949. Epub 2023 Sep 17.
The Michael J. Fox Foundation has been funding research on Parkinson's disease for 35 years, but has yet to find a cure. This is due to a problem with the philosophy behind the development of modern medical treatments. In this paper, we will introduce "smart medicine" with a substance that can solve all the problems of central nervous system drugs. The substance is the smallest diatomic molecule, the hydrogen molecule. Due to their size, hydrogen molecules can easily penetrate the cell membrane and enter the brain. In the midbrain of Parkinson's disease patients, hydroxyl radicals generated by the Fenton reaction cause a chain reaction of oxidation of dopamine, but hydrogen entering the midbrain can convert the hydroxyl radicals into water molecules and inhibit the oxidation of dopamine. In this paper, we focus on the etiology of neurological diseases, especially Parkinson's disease, and present a case in which hydrogen inhalation improves the symptoms of Parkinson's disease, such as body bending and hand tremor. And we confidently state that if Michael J. Fox encountered "smart medicine" that could be realized with molecular hydrogen, he would not be a "lucky man" but a "super-lucky man."
迈克尔·J·福克斯基金会（MJFF）已经在帕金森病研究领域投入了 35 年，但尚未找到治愈方法。这是由于现代医学治疗发展背后的理念存在问题。在本文中，我们将介绍一种“智能药物”，这种药物可以解决中枢神经系统药物的所有问题。这种物质是最小的双原子分子——氢分子。由于其体积小，氢分子可以轻松穿透细胞膜并进入大脑。在帕金森病患者的中脑中，由 Fenton 反应产生的羟基自由基引发多巴胺氧化的连锁反应，但进入中脑的氢可以将羟基自由基转化为水分子，从而抑制多巴胺的氧化。本文主要聚焦于神经疾病的病因，特别是帕金森病，并提出了一个病例，即吸入氢气可以改善帕金森病的症状，如身体弯曲和手部震颤。我们有信心地说，如果迈克尔·J·福克斯遇到了可以用分子氢实现的“智能药物”，他将不再是“幸运儿”，而是“超级幸运儿”。
