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青少年控制性药物依从性、治疗障碍和哮喘控制的差异。

Disparities in adolescent controller medication adherence, treatment barriers, and asthma control.

机构信息

Cincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, Cincinnati, Ohio, USA.

Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

出版信息

Pediatr Pulmonol. 2024 Dec;59(12):3288-3297. doi: 10.1002/ppul.27192. Epub 2024 Jul 29.

Abstract

BACKGROUND

Disparities in asthma persist despite advances in interventions. Adherence and self-management behaviors are critical yet challenging during adolescence. Treatment barriers include individual factors as well as structural and social determinants of health.

OBJECTIVE

To determine differences in controller medication adherence, asthma control, and treatment barriers by race, income, and insurance and whether racial disparities persist when controlling for income and insurance. Associations between adherence, barriers, and control were also examined.

METHODS

Adolescents completed measures of treatment barriers and asthma control. Controller medication adherence was measured electronically. Descriptive statistics, means comparisons, and analyses of covariance were conducted.

RESULTS

One hundred twenty-five adolescents participated (M = 14.55, SD = 2.01, 37.6% Black or African American, 55.2% White). Black or African American adolescents had significantly lower adherence than White adolescents, t(105) = 2.79, p = .006, Cohen's d = .55. This difference was not significant when controlling for income and insurance (p > .05). There was a significant difference in asthma control, F(1,86) = 4.07, p = .047, η  = .045, where Black or African American adolescents had better asthma control scores than White adolescents. Feeling tired of living with asthma was the most common barrier among all adolescents (62.4%). More Black or African American adolescents endorsed difficulty getting to the pharmacy than White adolescents, X (1, N = 116) = 4.86, p = .027.

CONCLUSIONS

Racial disparities in asthma may be partially driven by income, insurance, and pharmacy access. Asthma burnout may be important to address for all adolescents with asthma.

摘要

背景

尽管干预措施取得了进展,但哮喘仍存在差异。在青少年时期,坚持治疗和自我管理行为至关重要,但也极具挑战性。治疗障碍包括个人因素以及健康的结构和社会决定因素。

目的

确定种族、收入和保险对控制器药物依从性、哮喘控制和治疗障碍的差异,以及在控制收入和保险的情况下,种族差异是否仍然存在。还检查了坚持治疗、障碍和控制之间的关联。

方法

青少年完成了治疗障碍和哮喘控制的测量。通过电子方式测量控制器药物的依从性。进行了描述性统计、均值比较和协方差分析。

结果

125 名青少年参与了研究(M=14.55,SD=2.01,37.6%为黑种人或非裔美国人,55.2%为白种人)。与白种人青少年相比,黑种人或非裔美国人青少年的依从性明显较低,t(105)=2.79,p=0.006,Cohen's d=0.55。当控制收入和保险时,这种差异不显著(p>.05)。哮喘控制方面存在显著差异,F(1,86)=4.07,p=0.047,η 2=0.045,黑种人或非裔美国人青少年的哮喘控制得分好于白种人青少年。厌倦了与哮喘一起生活是所有青少年中最常见的障碍(62.4%)。与白种人青少年相比,更多的黑种人或非裔美国人青少年表示难以去药店,X(1,N=116)=4.86,p=0.027。

结论

哮喘方面的种族差异可能部分归因于收入、保险和药房的可及性。哮喘倦怠可能是所有哮喘青少年都需要解决的重要问题。

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本文引用的文献

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Asthma Surveillance - United States, 2006-2018.哮喘监测 - 美国,2006-2018 年。
MMWR Surveill Summ. 2021 Sep 17;70(5):1-32. doi: 10.15585/mmwr.ss7005a1.
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Treatment Adherence in Adolescents with Asthma.青少年哮喘患者的治疗依从性
J Asthma Allergy. 2020 Jan 14;13:39-49. doi: 10.2147/JAA.S233268. eCollection 2020.

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