Llamas-Esperón Guillermo A, Berrios-Bárcenas Enrique A, Cossío-Aranda Jorge E, Salmun-Nehmad Sylvia, Morales Flores Rahab A, Escalante-Seyffert Maria C, Leal-Cavazos Jorge, Sandoval-Rodríguez Eufracino, Pamplona-Ávila Eduardo, Sánchez-Hiza Enrique, Ramos-Villalobos Liliana E, Aguilera-Mora Luisa F, Benavides-González Mario A, Carrillo Carlos D, Llamas-Delgado Guillermo, Zaldívar-Zurita Jonathan H, Matadamas-Hernández Norberto
Hospital Cardiológica Aguascalientes, Aguascalientes, Mexico.
Instituto Nacional de Cardiología "Ignacio Chávez", Ciudad de México, Mexico.
Arch Cardiol Mex. 2024 Jul 29;95(1):18-25. doi: 10.24875/ACM.24000033.
The study aimed to know the clinical, demographic, diagnostic, and treatments characteristics in patients with cardiomyopathies in Mexico.
The Mexican Registry of Cardiomyopathies (REMEMI) is an observational, prospective and national study of patients with cardiomyopathies, which includes: Dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RCM) and arrhythmogenic cardiomyopathy of the right ventricle (ARVC).
A total of 1026 patients from most states of the Mexican Republic (19) were included, with 494 corresponding to DCM, 490 to HCM, 35 to RCM, and seven to ARVC. We found significant differences between the various cardiomyopathy phenotypes (p < 0.05) in the coexistence with diabetes, use of implantable defibrillator, presence of ventricular tachycardia, and NYHA functional class ≥ 1. There were no significant differences in age and predominant gender between each one. When analyzing by phenotype, we found that patients with HCM have limited use of diagnostic methods considered indispensable, such as cardiac magnetic resonance, Holter monitoring, and genetic testing in patients and their relatives.
Seeking contemporary information through observational registries in Mexico is a valuable opportunity to understand the characteristics of the methods used in the study and treatment of diseases such as cardiomyopathies by Mexican physicians. It can provide information for the implementation of management guidelines and strategies to disseminate findings to improve healthcare in our country.
本研究旨在了解墨西哥心肌病患者的临床、人口统计学、诊断和治疗特征。
墨西哥心肌病登记处(REMEMI)是一项针对心肌病患者的观察性、前瞻性全国性研究,其中包括:扩张型心肌病(DCM)、肥厚型心肌病(HCM)、限制型心肌病(RCM)和致心律失常性右室心肌病(ARVC)。
共纳入了来自墨西哥共和国19个州的1026例患者,其中494例为DCM,490例为HCM,35例为RCM,7例为ARVC。我们发现,在合并糖尿病、使用植入式除颤器、室性心动过速的存在以及纽约心脏协会(NYHA)功能分级≥1方面,不同心肌病表型之间存在显著差异(p<0.05)。各表型之间在年龄和主要性别方面无显著差异。按表型分析时,我们发现HCM患者对一些被认为必不可少的诊断方法,如心脏磁共振成像、动态心电图监测以及患者及其亲属的基因检测的使用有限。
通过墨西哥的观察性登记处获取当代信息,是了解墨西哥医生在研究和治疗心肌病等疾病时所用方法特征的宝贵机会。它可为实施管理指南和策略提供信息,以传播研究结果,改善我国的医疗保健。