Conroy Ellen R, Banzon Tina M, Simoneau Tregony, Phipatanakul Wanda, van Boven Job F M, Larenas-Linnemann Désirée
Division of Immunology, Department of Medicine, Boston Children's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.
Harvard Medical School, Boston, Mass; Division of Pulmonology, Department of Medicine, Boston Children's Hospital, Boston, Mass.
J Allergy Clin Immunol Pract. 2024 Dec;12(12):3180-3188. doi: 10.1016/j.jaip.2024.07.018. Epub 2024 Jul 27.
Asthma, allergic rhinitis, and food allergy are common allergic diseases, yet adherence to many management options remains poor, leading to worse health outcomes and financial implications for society and health systems. The underlying causes of nonadherence are numerous, ranging from patient-specific factors to broader socioeconomic and systems-based factors. In this review, we aim to discuss the definition of adherence, which can be divided into 3 components: initiation, implementation, and persistence, as well as to review various methods of measuring adherence. Subsequently, we will review the epidemiology of adherence to asthma and allergic rhinitis medications, allergen immunotherapy, and oral immunotherapy. Finally, we will discuss the multifaceted etiology of poor adherence and its subsequent impact on patients and society.
哮喘、过敏性鼻炎和食物过敏是常见的过敏性疾病，但许多治疗方案的依从性仍然很差，导致健康状况恶化，并给社会和卫生系统带来经济负担。不依从的根本原因众多，从患者个体因素到更广泛的社会经济和基于系统的因素都有。在本综述中，我们旨在讨论依从性的定义，其可分为三个组成部分：起始、实施和持续，同时回顾测量依从性的各种方法。随后，我们将综述哮喘和过敏性鼻炎药物、变应原免疫疗法及口服免疫疗法的依从性流行病学。最后，我们将讨论依从性差的多方面病因及其对患者和社会的后续影响。
