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去骨瓣减压术在急性暴发性脑水肿中的应用。

Decompressive craniectomy in the acute fulminant cerebral edema.

机构信息

Departamento de Neurocirugía, Hospital Universitario Central de Asturias, Asturias, Spain.

Sección de Cuidados Intensivos Pediátricos, Hospital Universitario Central de Asturias, Asturias, Spain.

出版信息

Neurocirugia (Astur : Engl Ed). 2024 Nov-Dec;35(6):329-333. doi: 10.1016/j.neucie.2024.07.008. Epub 2024 Jul 27.

Abstract

Acute fulminant cerebral edema is a type of rapidly progressive encephalitis that occurs in children and is associated with significant morbidity and mortality. We present a clinical case with seizures, rapid neurological deterioration and the early appearance of cerebral herniation signs. Although the radiological tests were initially normal and there are no established parameters that predict the evolution of encephalitis to a rapidly progressive subtype, the clinical evolution forced to consider the decompressive craniectomy due to the lack of response to the medical management of the cerebral edema. It may be necessary take a brain biopsy to confirm the etiology of the encephalitis origin of acute fulminant cerebral edema. The objective of surgery should be not only to increase survival, but also to reduce subsequent neurological sequelae.

摘要

急性暴发性脑肿胀是一种在儿童中发生的迅速进展性脑炎,其与较高的发病率和死亡率相关。我们呈现了一例以癫痫发作、神经功能快速恶化和早期出现脑疝体征为特征的临床病例。尽管最初的影像学检查正常,也没有既定的参数可以预测脑炎向迅速进展型演变,但由于脑水肿的药物治疗反应不佳,临床进展迫使我们考虑去颅骨减压术。可能有必要进行脑活检以明确急性暴发性脑肿胀的脑炎病因。手术的目的不仅应是提高生存率,还应降低后续的神经后遗症。

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