Universidad César Vallejo, Health Sciences Faculty, Trujillo, Peru.
Instituto Nacional de Ciencias Neurológicas, Epilepsy Department, Lima, Peru.
Arq Neuropsiquiatr. 2024 Jul;82(7):1-7. doi: 10.1055/s-0044-1788584. Epub 2024 Jul 29.
Arteritis is a complication of neurocysticercosis (NCC), which is not well known and could trigger strokes. The transcranial Doppler ultrasound (TCD) is a noninvasive method for detecting, staging, and monitoring cerebrovascular diseases. Nonetheless, the utility of TCD to evaluate cerebral hemodynamic changes, suggesting vasculitis associated with NCC remains uncertain.
To evaluate cerebral hemodynamic changes using TCD in patients with subarachnoid and parenchymal NCC.
There were 53 patients with NCC evaluated at a reference hospital for neurological diseases included (29 with subarachnoid and 24 with parenchymal). Participants underwent a clinical interview and serology for cysticercosis and underwent TCD performed within 2 weeks of enrollment. Mean flow velocity, peak systolic velocity, end diastolic velocity, and pulsatility index were recorded.
Among the participants, there were 23 (43.4%) women, with a median age of 37 years (IQR: 29-48). Cerebral hemodynamic changes suggesting vasculitis were detected in 12 patients (22.64%); the most compromised vessel was the middle cerebral artery in 11 (91.67%) patients. There were more females in the group with sonographic signs of vasculitis (10/12, 83.33% vs. 13/41, 31.71%; = 0.002), and this was more frequent in the subarachnoid NCC group (9/29, 31.03% vs. 3/24, 12.5%; = 0.187), although this difference did not reach statistical significance.
Cerebral hemodynamic changes suggestive of vasculitis are frequent in patients with NCC and can be evaluated using TCD.
动脉炎是神经囊尾蚴病（NCC）的一种并发症，它并不广为人知，却可能引发中风。经颅多普勒超声（TCD）是一种用于检测、分期和监测脑血管疾病的非侵入性方法。然而，TCD 用于评估与 NCC 相关的血管炎引起的脑血流动力学变化的效用尚不确定。
评估蛛网膜下腔和实质 NCC 患者的脑血流动力学变化。
在一家神经病学参考医院，对 53 名 NCC 患者进行评估（29 名蛛网膜下腔和 24 名实质）。参与者接受临床访谈和囊尾蚴血清学检查，并在入组后 2 周内进行 TCD 检查。记录平均流速、收缩期峰值流速、舒张末期流速和搏动指数。
参与者中，有 23 名（43.4%）女性，中位年龄为 37 岁（IQR：29-48）。12 名患者（22.64%）检测到提示血管炎的脑血流动力学变化；最受影响的血管是 11 名（91.67%）患者的大脑中动脉。在有超声血管炎迹象的患者中，女性更多（10/12，83.33% vs. 13/41，31.71%；=0.002），在蛛网膜下腔 NCC 组中更常见（9/29，31.03% vs. 3/24，12.5%；=0.187），尽管这一差异没有达到统计学意义。
NCC 患者常出现提示血管炎的脑血流动力学变化，可通过 TCD 进行评估。
