Department of Neurology, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, Tamil Nadu, India
Department of Neurology, Sri Ramachandra Institute of Higher Education and Research (Deemed to be University), Chennai, Tamil Nadu, India.
BMJ Case Rep. 2024 Jul 29;17(7):e260998. doi: 10.1136/bcr-2024-260998.
SummaryShapiro's syndrome is a rare neurological disease. The triad of Shapiro's syndrome includes episodes of hyperhidrosis, hypothermia and complete/partial agenesis of the corpus callosum. We report a case of a young male who had episodic chills, increased sweating and fatigue. During these episodes, he was found to have bradycardia, hypotension and hypothermia. Clinical and neurological examinations were unremarkable. The MRI of the brain revealed agenesis of the corpus callosum. There was a good response to carbamazepine therapy.
Shapiro 综合征是一种罕见的神经疾病。Shapiro 综合征的三联征包括多汗症、低温和胼胝体完全/部分发育不全。我们报告了一例年轻男性患者，他间歇性寒战、多汗和疲劳。在这些发作期间，他被发现心动过缓、低血压和低温。临床和神经系统检查无明显异常。脑部 MRI 显示胼胝体发育不全。卡马西平治疗反应良好。
