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冠状动脉生理学在慢性冠状动脉综合征患者管理中的作用是什么?

What is the Role of Coronary Physiology in the Management of Patients with Chronic Coronary Syndromes?

作者信息

Saunders Alec, Curzen Nick

机构信息

Faculty of Medicine, University of Southampton, SO17 1BJ Southampton, UK.

Cardiothoracic Care Group, University Hospital Southampton NHS Trust, SO16 6YD Southampton, UK.

出版信息

Rev Cardiovasc Med. 2022 Apr 13;23(4):145. doi: 10.31083/j.rcm2304145. eCollection 2022 Apr.

DOI:10.31083/j.rcm2304145
PMID:39076213
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11273976/
Abstract

The use of coronary physiology in patients with chronic coronary syndromes is highly variable, and the evidence base complex. Tests of coronary physiology have traditionally been invasive (e.g., fractional flow reserve), but novel non-invasive methods are now available which provide additional anatomical information (e.g., computed tomography-based fractional flow reserve and angiogram-derived physiology). This review summarises the evidence for and against the relative value of these tests for patients being investigated for chest pain that may represent chronic coronary syndromes, and for those triaged to percutaneous coronary intervention.

摘要

慢性冠状动脉综合征患者冠状动脉生理学的应用差异很大,证据基础也很复杂。传统上,冠状动脉生理学检测是侵入性的(例如,血流储备分数),但现在有了新的非侵入性方法,可提供额外的解剖学信息(例如,基于计算机断层扫描的血流储备分数和血管造影衍生的生理学)。本综述总结了这些检测对于可能代表慢性冠状动脉综合征的胸痛患者以及那些被分诊接受经皮冠状动脉介入治疗的患者的相对价值的支持和反对证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97cf/11273976/8eeddfbf2f05/2153-8174-23-4-145-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97cf/11273976/81f90a494cfa/2153-8174-23-4-145-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97cf/11273976/8eeddfbf2f05/2153-8174-23-4-145-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97cf/11273976/81f90a494cfa/2153-8174-23-4-145-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97cf/11273976/8eeddfbf2f05/2153-8174-23-4-145-g2.jpg

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本文引用的文献

1
Atheroma or ischemia: which is more important for managing patients with stable chest pain?动脉粥样硬化还是缺血:对于稳定型胸痛患者的管理,哪个更重要?
Future Cardiol. 2022 May;18(5):417-429. doi: 10.2217/fca-2021-0053. Epub 2022 Apr 1.
2
Fractional Flow Reserve-Guided PCI as Compared with Coronary Bypass Surgery.《血流储备分数指导下的 PCI 与冠状动脉旁路移植术的比较》。
N Engl J Med. 2022 Jan 13;386(2):128-137. doi: 10.1056/NEJMoa2112299. Epub 2021 Nov 4.
3
Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity.
基于冠状动脉疾病和缺血严重程度的 ISCHEMIA 试验结果。
Circulation. 2021 Sep 28;144(13):1024-1038. doi: 10.1161/CIRCULATIONAHA.120.049755. Epub 2021 Sep 9.
4
Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT-FFR trial.薄帽纤维粥样斑块可预测正常血流储备分数的糖尿病患者的临床事件:COMBINE OCT-FFR 试验。
Eur Heart J. 2021 Dec 1;42(45):4671-4679. doi: 10.1093/eurheartj/ehab433.
5
Fractional flow reserve derived from computed tomography coronary angiography in the assessment and management of stable chest pain: the FORECAST randomized trial.基于 CT 冠状动脉成像的血流储备分数在稳定型胸痛评估和管理中的应用:FORECAST 随机试验。
Eur Heart J. 2021 Oct 1;42(37):3844-3852. doi: 10.1093/eurheartj/ehab444.
6
Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction.多支血管 PCI 血运重建:以血流储备分数(FFR)或血管造影为指导治疗心肌梗死。
N Engl J Med. 2021 Jul 22;385(4):297-308. doi: 10.1056/NEJMoa2104650. Epub 2021 May 16.
7
Fractional flow reserve guided versus angiographic guided surgical revascularization: A meta-analysis.分流量储备引导与血管造影引导的手术血运重建:荟萃分析。
Catheter Cardiovasc Interv. 2021 Jul 1;98(1):E18-E23. doi: 10.1002/ccd.29427. Epub 2020 Dec 14.
8
The Impact of Coronary Physiology on Contemporary Clinical Decision Making.冠状动脉生理学对当代临床决策的影响。
JACC Cardiovasc Interv. 2020 Jul 27;13(14):1617-1638. doi: 10.1016/j.jcin.2020.04.040.
9
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10
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