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免疫功能正常患者的胸椎孤立性隐球菌感染

Isolated Cryptococcal Infection of the Thoracic Spine in an Immunocompetent Patient.

作者信息

Pi Wensen, Liu Yang, Chen Haidan, Zhao Hongwei

机构信息

Department of Spine Surgery of Yichang Central People's Hospital, First Clinical Medical College of China Three Gorges University, Yichang, Hubei, 443000, People's Republic of China.

出版信息

Infect Drug Resist. 2024 Jul 24;17:3219-3224. doi: 10.2147/IDR.S472521. eCollection 2024.

DOI:10.2147/IDR.S472521
PMID:39076349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11284138/
Abstract

Cryptococcus neoformans is a type of fungal infection, which primarily affects the central nervous system and lungs of immunocompromised individuals. Spinal infections are known to be a rare manifestation of cryptococcosis. Herein, we report a case of a patient with isolated nonspecific spinal lesions at the T10 vertebra. The patient received non-surgical treatment with antifungal drugs, resulting in satisfactory clinical outcomes.

摘要

新型隐球菌是一种真菌感染类型，主要影响免疫功能低下个体的中枢神经系统和肺部。脊髓感染是已知的隐球菌病罕见表现形式。在此，我们报告一例在T10椎体出现孤立性非特异性脊髓病变的患者。该患者接受了抗真菌药物的非手术治疗，临床结果令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/f91d82f1afc8/IDR-17-3219-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/0d032df48f76/IDR-17-3219-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/4dac040a212b/IDR-17-3219-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/51cf3e851c02/IDR-17-3219-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/a9bd24a12a13/IDR-17-3219-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/f91d82f1afc8/IDR-17-3219-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/0d032df48f76/IDR-17-3219-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/4dac040a212b/IDR-17-3219-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/51cf3e851c02/IDR-17-3219-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/a9bd24a12a13/IDR-17-3219-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5eec/11284138/f91d82f1afc8/IDR-17-3219-g0005.jpg

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本文引用的文献

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Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.全球隐球菌病诊断和管理指南：欧洲癌症研究与治疗组织和国际系统性真菌感染学会与美国微生物学会合作开展的一项倡议。
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Isolated cryptococcal osteomyelitis of the sacrum in an immunocompetent patient: a case report and literature review.免疫功能正常患者孤立性 cryptococcal 骨髓炎：病例报告及文献复习。
BMC Infect Dis. 2023 Feb 24;23(1):116. doi: 10.1186/s12879-023-08066-6.
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免疫功能正常患者的耻骨隐球菌骨髓炎：一例报告及近期文献综述
Infect Drug Resist. 2022 Dec 14;15:7369-7375. doi: 10.2147/IDR.S390881. eCollection 2022.
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Disseminated Cryptococcal Infection of the Lumbar Spine in an Immunocompetent Man.一名免疫功能正常男性的腰椎播散性隐球菌感染
Infect Drug Resist. 2022 Aug 4;15:4229-4234. doi: 10.2147/IDR.S359612. eCollection 2022.
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A holistic review on Cryptococcus neoformans.新型隐球菌的全面综述。
Microb Pathog. 2022 May;166:105521. doi: 10.1016/j.micpath.2022.105521. Epub 2022 Apr 15.
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Transverse Myelitis Associated with in an Immunocompetent Patient.一名免疫功能正常患者中与[具体病症]相关的横贯性脊髓炎 。 （你提供的原文“Transverse Myelitis Associated with in an Immunocompetent Patient.”中“associated with”后面缺少具体内容，所以翻译出来不太完整，你可以补充完整后让我继续为你准确翻译。）
Case Rep Infect Dis. 2022 Feb 21;2022:2000246. doi: 10.1155/2022/2000246. eCollection 2022.
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Human immune polymorphisms associated with the risk of cryptococcal disease.与新型隐球菌病风险相关的人类免疫多态性。
Immunology. 2022 Feb;165(2):143-157. doi: 10.1111/imm.13425. Epub 2021 Nov 11.
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Cryptococcosis complicating diabetes mellitus: a scoping review.隐球菌病合并糖尿病：一项范围综述
Ther Adv Infect Dis. 2021 May 5;8:20499361211014769. doi: 10.1177/20499361211014769. eCollection 2021 Jan-Dec.
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Possible environmental exposure-associated pulmonary cryptococcosis in a patient with rheumatoid arthritis: a case report and literature review.类风湿关节炎患者中可能与环境暴露相关的肺隐球菌病：一例报告及文献复习
J Int Med Res. 2020 Oct;48(10):300060520962302. doi: 10.1177/0300060520962302.
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Cryptococcal osteomyelitis of the Zygomatic bone: a case report.颧骨 cryptococcal 骨髓炎：一例报告。
BMC Infect Dis. 2020 Jun 5;20(1):399. doi: 10.1186/s12879-020-05123-2.