Smalcova Jana, Belohlavek Jan
Anaesthesiology and Resuscitation Department, Cardiac Centre, Institute for Clinical and Experimental Medicine, 14000 Prague, Czech Republic.
First Faculty of Medicine, Charles University, 12108 Prague, Czech Republic.
Rev Cardiovasc Med. 2023 Sep 19;24(9):262. doi: 10.31083/j.rcm2409262. eCollection 2023 Sep.
Non-occlusive mesenteric ischemia (NOMI) is a severe complication in patients after cardiac arrest (CA). The diagnosis is complicated, the treatment options are limited. Given the susceptibility of enterocytes to ischemia, the incidence and severity of NOMI in the post-resuscitation period may reflect the intensity and duration of both ischemia and subsequent reperfusion injury. NOMI is considered to be associated with adverse neurological outcomes in CA patients. Therefore, NOMI should not only be regarded as a post-resuscitation complication but also as one of the prognostic markers in CA patients.This paper summarizes current knowledge on NOMI's pathophysiology, diagnosis, treatment, and prognostic significance in CA patients.
非闭塞性肠系膜缺血(NOMI)是心脏骤停(CA)患者的一种严重并发症。其诊断复杂,治疗选择有限。鉴于肠上皮细胞对缺血的易感性,复苏后期NOMI的发生率和严重程度可能反映缺血及随后再灌注损伤的强度和持续时间。NOMI被认为与CA患者不良神经预后相关。因此,NOMI不仅应被视为复苏后并发症,还应被视为CA患者的预后标志物之一。本文总结了目前关于NOMI在CA患者中的病理生理学、诊断、治疗及预后意义的知识。