Apostolovic Svetlana, Maricic Bojan, Bozinovic Nenad, Kostic Tomislav, Perisic Zoran, Djokovic Aleksandra, Bojanovic Mihajlo, Petrovic Milovan, Stankovic Goran
Department of Cardiology, Division of Interventional Cardiology, University Clinical Center Nis, 18000 Nis, Serbia.
Faculty of Medicine, Department of Internal Medicine, University of Nis, 18000 Nis, Serbia.
Rev Cardiovasc Med. 2023 Aug 17;24(8):235. doi: 10.31083/j.rcm2408235. eCollection 2023 Aug.
Spontaneous coronary artery dissection (SCAD) is a non-traumatic, non-atherosclerotic layering of the coronary artery wall due to the presence of a subintimal hematoma or an intimal tear with the creation of a false lumen that compresses the true lumen and restricts or obstructs the flow. Patients with SCAD and preserved coronary flow are treated conservatively according to the general recommendations. However, percutaneous coronary intervention should be considered in patients with artery occlusion and/or refractory ischemia. Stenting is associated with increased risks comprising stenting in the false lumen, in-stent thrombosis, and/or stent malappositon as well as antegrade or retrograde propagation of the intramural hematoma. Intracoronary imaging is of great value both for the diagnosis and treatment of SCAD. There is rising scrutiny on the use of cutting balloons in acute coronary syndrome caused by SCAD. The idea of using cutting balloons is to fenestrate the intima and drain the intramural hematoma. Our review presents an analysis of 17 published cases of cutting balloon (CB) use in SCAD. What is encouraging is that of the 12 published cases, in 11 Thrombolysis in Myocardial Infarction (TIMI) 3 flow was established with this technique, and TIMI 2 flow in one, without subsequent stent implantation. Four patients received a stent after the CB use, while one patient underwent CB angioplasty after hematoma propagation caused by stent implantation. In all cases, patients were asymptomatic at follow-up, with TIMI 3 flow.
自发性冠状动脉夹层(SCAD)是一种非创伤性、非动脉粥样硬化性的冠状动脉壁分层,原因是存在内膜下血肿或内膜撕裂并形成假腔,假腔压迫真腔并限制或阻碍血流。SCAD且冠状动脉血流保留的患者按照一般建议进行保守治疗。然而,对于动脉闭塞和/或难治性心肌缺血的患者应考虑进行经皮冠状动脉介入治疗。支架置入术存在增加的风险,包括在假腔内置入支架、支架内血栓形成和/或支架贴壁不良,以及壁内血肿的顺行或逆行扩展。冠状动脉内成像对SCAD的诊断和治疗都具有重要价值。对于SCAD引起的急性冠状动脉综合征中切割球囊的使用,审查日益严格。使用切割球囊的目的是切开内膜并引流壁内血肿。我们的综述对17例已发表的在SCAD中使用切割球囊(CB)的病例进行了分析。令人鼓舞的是,在12例已发表的病例中,有11例通过该技术实现了心肌梗死溶栓(TIMI)3级血流,1例为TIMI 2级血流,且无需后续置入支架。4例患者在使用CB后接受了支架置入,而1例患者在支架置入导致血肿扩展后接受了CB血管成形术。在所有病例中,患者在随访时均无症状,TIMI血流为3级。