高血压性心脏病：机制、诊断与治疗
Hypertensive Heart Disease: Mechanisms, Diagnosis and Treatment.
作者信息
Huang Xuewei, Hu Lizhi, Long Zhuojun, Wang Xinyao, Wu Junru, Cai Jingjing
机构信息
Department of Cardiology, The Third Xiangya Hospital, Central South University, 410013 Changsha, Hunan, China.
Xiangya School of Medicine, Central South University, 410013 Changsha, Hunan, China.
出版信息
Rev Cardiovasc Med. 2024 Mar 6;25(3):93. doi: 10.31083/j.rcm2503093. eCollection 2024 Mar.
Hypertensive heart disease (HHD) presents a substantial global health burden, spanning a spectrum from subtle cardiac functional alterations to overt heart failure. In this comprehensive review, we delved into the intricate pathophysiological mechanisms governing the onset and progression of HHD. We emphasized the significant role of neurohormonal activation, inflammation, and metabolic remodeling in HHD pathogenesis, offering insights into promising therapeutic avenues. Additionally, this review provided an overview of contemporary imaging diagnostic tools for precise HHD severity assessment. We discussed in detail the current potential treatments for HHD, including pharmacologic, lifestyle, and intervention devices. This review aimed to underscore the global importance of HHD and foster a deeper understanding of its pathophysiology, ultimately contributing to improved public health outcomes.
高血压性心脏病（HHD）给全球带来了沉重的健康负担，涵盖了从轻微心脏功能改变到明显心力衰竭的一系列情况。在这篇全面综述中，我们深入探究了支配HHD发生和发展的复杂病理生理机制。我们强调了神经激素激活、炎症和代谢重塑在HHD发病机制中的重要作用，为有前景的治疗途径提供了见解。此外，本综述概述了用于精确评估HHD严重程度的当代影像学诊断工具。我们详细讨论了HHD目前的潜在治疗方法，包括药物、生活方式和介入装置。本综述旨在强调HHD在全球范围内的重要性，并促进对其病理生理学的更深入理解，最终有助于改善公共卫生成果。
Zotero 插件