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关节穿刺术前抗生素治疗对滑液细胞计数及鉴别诊断原发性关节化脓性关节炎的影响。

Effect of Antibiotic Therapy Before Arthrocentesis on Synovial Fluid Cell Count and Differential for Diagnosis of Native Joint Septic Arthritis.

作者信息

Khodadadi Ryan B, Damronglerd Pansachee, McHugh Jack W, El Zein Said, Lahr Brian D, Yuan Brandon J, Abu Saleh Omar M, Suh Gina A, Tande Aaron J

机构信息

Division of Public Health, Infectious Diseases, and Occupational Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Division of Infectious Diseases, Department of Internal Medicine, Thammasat University, Pathum Thani, Thailand.

出版信息

Open Forum Infect Dis. 2024 Jul 19;11(7):ofae403. doi: 10.1093/ofid/ofae403. eCollection 2024 Jul.

Abstract

We examined the effect of preoperative antibiotic exposure and duration on synovial fluid samples from patients with native joint septic arthritis of the hip/knee. While exposure before diagnostic arthrocentesis did not affect fluid parameters, increased duration was associated with a decreased total nucleated cell count, underscoring the complex antibiotic effects on synovial fluid parameters.

摘要

我们研究了术前抗生素暴露及其持续时间对髋/膝关节原发性化脓性关节炎患者滑液样本的影响。虽然诊断性关节穿刺术前的抗生素暴露不影响滑液参数,但暴露持续时间增加与总核细胞计数减少相关,这突出了抗生素对滑液参数的复杂影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec86/11285182/d2bf5c72c380/ofae403_ga.jpg

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