新冠疫情期间大型与小型心脏病科急性心力衰竭患者住院时间延长及院内死亡率更高：COV-HF-SIRIO 6多中心研究的亚分析

Longer Hospitalizations and Higher In-Hospital Mortality for Acute Heart Failure during the COVID-19 Pandemic in Larger vs. Smaller Cardiology Departments: Subanalysis of the COV-HF-SIRIO 6 Multicenter Study.

作者信息

Ostrowska Małgorzata, Kasprzak Michał, Stolarek Wioleta, Grzelakowska Klaudyna, Kryś Jacek, Kubica Aldona, Adamski Piotr, Podhajski Przemysław, Navarese Eliano Pio, Anielska-Michalak Edyta, Matuszewska-Brycht Oliwia, Curzytek Andrzej, Dudek Aneta, Gromadziński Leszek, Grzelakowski Paweł, Kamiński Leszek, Kleinrok Andrzej, Kostkiewicz Marcin, Koziński Marek, Król Paweł, Kulawik Tomasz, Minczew Gleb, Mindykowski Marcin, Pawlak Agnieszka, Prokopczuk Janusz, Skonieczny Grzegorz, Sobkowicz Bożena, Sowiński Sergiusz, Stankala Sebastian, Szymański Paweł, Wester Andrzej, Wilczewski Przemysław, Bartuś Stanisław, Budaj Andrzej, Gajda Robert, Gąsior Mariusz, Gruchała Marcin, Droźdź Jarosław, Jaguszewski Miłosz, Jankowski Piotr, Legutko Jacek, Lesiak Maciej, Leszek Przemysław, Mitkowski Przemysław, Nessler Jadwiga, Tomaszuk-Kazberuk Anna, Tycińska Agnieszka, Zdrojewski Tomasz, Kaźmierczak Jarosław, Kubica Jacek

机构信息

Collegium Medicum, Nicolaus Copernicus University, 85-094 Bydgoszcz, Poland.

Department of Cardiology, Marian Zyndram-Kościałkowski Ministry of Interior and Administration Hospital, 15-471 Białystok, Poland.

出版信息

Rev Cardiovasc Med. 2022 Aug 24;23(9):292. doi: 10.31083/j.rcm2309292. eCollection 2022 Sep.

DOI:10.31083/j.rcm2309292

PMID:39077718

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11262386/

Abstract

BACKGROUND

The coronavirus disease-2019 (COVID-19) pandemic is surging across Poland, leading to many direct deaths and underestimated collateral damage. We aimed to compare the influence of the COVID-19 pandemic on hospital admissions and in-hospital mortality in larger vs. smaller cardiology departments (i.e., with 2000 vs. 2000 hospitalizations per year in 2019).

METHODS

We performed a subanalysis of the COV-HF-SIRIO 6 multicenter retrospective study including all patients hospitalized in 24 cardiology departments in Poland between January 1, 2019 and December 31, 2020, focusing on patients with acute heart failure (AHF) and COVID-19.

RESULTS

Total number of hospitalizations was reduced by 29.2% in larger cardiology departments and by 27.3% in smaller cardiology departments in 2020 vs. 2019. While hospitalizations for AHF were reduced by 21.8% and 25.1%, respectively. The length of hospital stay due to AHF in 2020 was 9.6 days in larger cardiology departments and 6.6 days in smaller departments ( 0.001). In-hospital mortality for AHF during the COVID-19 pandemic was significantly higher in larger vs. smaller cardiology departments (10.7% vs. 3.2%; 0.001). In-hospital mortality for concomitant AHF and COVID-19 was extremely high in larger and smaller cardiology departments accounting for 31.3% vs. 31.6%, respectively.

CONCLUSIONS

During the COVID-19 pandemic longer hospitalizations and higher in-hospital mortality for AHF were observed in larger vs. smaller cardiology departments. Reduced hospital admissions and extremely high in-hospital mortality for concomitant AHF and COVID-19 were noted regardless of department size.

摘要

背景

2019冠状病毒病（COVID-19）大流行正在波兰蔓延，导致许多直接死亡和被低估的间接损害。我们旨在比较COVID-19大流行对大型与小型心脏病学部门住院人数和院内死亡率的影响（即2019年每年住院人数分别为2000例及以上与2000例以下）。

方法

我们对COV-HF-SIRIO 6多中心回顾性研究进行了亚分析，该研究纳入了2019年1月1日至2020年12月31日期间在波兰24个心脏病学部门住院的所有患者，重点关注急性心力衰竭（AHF）和COVID-19患者。

结果

与2019年相比，2020年大型心脏病学部门的住院总数减少了29.2%，小型心脏病学部门减少了27.3%。而AHF住院人数分别减少了21.8%和25.1%。2020年大型心脏病学部门因AHF的住院时间为9.6天，小型部门为6.6天（P<0.001）。在COVID-19大流行期间，大型心脏病学部门AHF的院内死亡率显著高于小型部门（10.7%对3.2%；P<0.001）。大型和小型心脏病学部门中AHF合并COVID-19的院内死亡率极高，分别为31.3%和31.6%。