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添加银和变形参数对锌基可生物降解合金的机械结构、生物降解性、抗菌性和力学性能的影响。

The effect of Silver addition and deformation parameters on mechanostructure, biodegradation, antimicrobial and mechanical properties of Zn-based biodegradable alloys.

机构信息

Department of Aircraft Airframe-Engine, School of Aviation, Firat University, Elazig, Turkey.

Department of Mechanical Engineering, Faculty of Engineering, Ataturk University, Erzurum, Turkey.

出版信息

J Biomater Appl. 2024 Oct;39(4):298-316. doi: 10.1177/08853282241268682. Epub 2024 Jul 30.

DOI:10.1177/08853282241268682
PMID:39077998
Abstract

Although low mechanical properties, Zinc (Zn) alloy systems with Copper (Cu) and Silver (Ag) as alloying elements have strong biocompatibility and biodegradability characteristics. This study examined the effects of rolling parameters and Ag alloying on the mechanical, biodegradable, and final structure of an alloy based on Zn. Comparing treated and untreated specimens, the addition of Ag led to a considerable improvement in both hardness and compressive strength. The produced alloys with varying amounts of Ag (between 1 and 4 wt%) were cold rolled at 400-800 r/min and friction coefficients between 0.3 and 0.5. The alloys' ultimate strength rose with an increase in rolling speed for Zn1Cu4Ag, and hardness and compressive strengths rose to 80HV and 470 MPa, respectively. It was demonstrated that rolling force rose somewhat with Ag concentration but significantly increased with rolling speed and friction. E. Coli and were used to assess the biodegradable alloys' antibacterial properties. For the Zn-1Cu-2Ag alloy, the inclusion of Ag resulted in a considerable (50%) rise in antibacterial activity that exceeded the effects seen in other alloy systems.

摘要

虽然锌(Zn)合金系统的机械性能较低,但由于其含有铜(Cu)和银(Ag)等合金元素,因此具有很强的生物相容性和可生物降解性。本研究探讨了轧制参数和 Ag 合金化对 Zn 基合金的机械性能、可生物降解性和最终结构的影响。与未经处理的试样相比,Ag 的添加使得硬度和抗压强度都有了显著提高。在 400-800r/min 的轧制速度和 0.3-0.5 的摩擦系数下,对添加了不同量(1-4wt%)Ag 的合金进行了冷轧。Zn1Cu4Ag 合金的屈服强度随轧制速度的增加而升高,硬度和抗压强度分别升高到 80HV 和 470MPa。结果表明,轧制力随 Ag 浓度略有增加,但随轧制速度和摩擦显著增加。采用大肠杆菌和金黄色葡萄球菌来评估可生物降解合金的抗菌性能。对于 Zn-1Cu-2Ag 合金,Ag 的加入使抗菌活性显著提高(50%),超过了其他合金系统的效果。

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