Universiti Malaya Eye Research Centre, Department of Ophthalmology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Institute of Mathematical Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia.
Indian J Ophthalmol. 2024 Aug 1;72(8):1118-1123. doi: 10.4103/IJO.IJO_2662_23. Epub 2024 Jul 29.
To evaluate the variation and stability of the posterior cornea surface parameters (posterior cornea curvature [PCC], posterior cornea astigmatism [PCA], and posterior cornea elevation [PCE]) after femtosecond laser-assisted in situ keratomileusis (LASIK) in patients with myopia and myopic astigmatism over a period of 6 months or longer.
This retrospective study comprised 284 right eyes. Patients aged 18 years or older with myopia up to -12.00 D and/or astigmatism up to -6.00 DC and who underwent femtosecond LASIK were recruited. Patients were divided into three subgroups: low myopia (-0.50 to -3.00 D), moderate myopia (>-3.00 to ≤-6.00 D), and high myopia (>-6.00 D), according to their pre-LASIK spherical equivalent (SE). The variables included for analysis were PCC (central 0-3.0 mm, pericentral 3.0-6.0 mm, and peripheral region 6.0-9.0 mm), PCE, PCA, internal anterior chamber depth, intraocular pressure, and central cornea thickness at the pre- and post-LASIK stages.
The central PCC remained unchanged across all three myopia subgroups at 1 month when compared to the pre-LASIK stage and remained stable at 6 months. The pericentral regions became flatter across all myopia subgroups at 1 month postsurgery (P < 0.001) and remained unchanged at 6 months. This trend was not seen in the peripheral cornea regions, which remained unchanged at 1 and 6 months post-LASIK when compared to pre-LASIK mean readings. There were minimal changes in post-LASIK posterior cornea astigmatism throughout follow-up. There was no incidence of post-LASIK surgery ectasia in this study population.
Post-LASIK, the different cornea subregions behaved differently. Overall, the posterior cornea surface remained stable post-LASIK across all myopia subgroups throughout follow-up.
评估近视和近视散光患者在接受飞秒激光辅助原位角膜磨镶术（LASIK）后 6 个月或更长时间内，后角膜表面参数（后角膜曲率[PCC]、后角膜散光[PCA]和后角膜高度[PCE]）的变化和稳定性。
本回顾性研究共纳入 284 只右眼。纳入年龄在 18 岁及以上，近视屈光度在-12.00 D 以内，散光屈光度在-6.00 DC 以内，并接受飞秒 LASIK 手术的患者。患者根据术前等效球镜（SE）分为三组：低度近视组（-0.50 至-3.00 D）、中度近视组（>-3.00 至≤-6.00 D）和高度近视组（>-6.00 D）。分析的变量包括 PCC（中央 0-3.0mm、旁中央 3.0-6.0mm 和周边 6.0-9.0mm）、PCE、PCA、前房内深度、眼压和中央角膜厚度在术前和术后阶段。
与术前相比，所有三组近视患者在术后 1 个月时中央 PCC 均保持不变，且在术后 6 个月时保持稳定。所有近视亚组的旁中央区域在术后 1 个月时变平坦（P < 0.001），而在术后 6 个月时则保持不变。这种趋势在周边角膜区域并未出现，术后 1 个月和 6 个月与术前平均读数相比保持不变。术后后角膜散光变化较小。在本研究人群中，没有发生术后 LASIK 扩张。
LASIK 术后，不同角膜亚区表现不同。总体而言，在后角膜表面在整个随访期间，所有近视亚组在 LASIK 术后均保持稳定。
