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产后20 - 26年的尿失禁、粪失禁和盆腔器官脱垂症状:一项纵向队列研究。

Urinary incontinence, faecal incontinence and pelvic organ prolapse symptoms 20-26 years after childbirth: A longitudinal cohort study.

作者信息

Hagen S, Sellers C, Elders A, Glazener C, MacArthur C, Toozs-Hobson P, Hemming C, Herbison P, Wilson D

机构信息

Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK.

Health Services Research Unit, University of Aberdeen, Aberdeen, UK.

出版信息

BJOG. 2024 Dec;131(13):1815-1823. doi: 10.1111/1471-0528.17913. Epub 2024 Jul 30.

DOI:10.1111/1471-0528.17913
PMID:39079703
Abstract

OBJECTIVE

To investigate pelvic floor dysfunction (PFD; urinary incontinence (UI), faecal incontinence (FI) and prolapse) ≥20 years after childbirth and their association with delivery mode history and demographic characteristics.

DESIGN

Cohort study with long-term follow-up.

SETTING

Maternity units in Aberdeen and Birmingham (UK) and Dunedin (NZ).

POPULATION

Women giving birth in 1993/1994.

METHODS

Postal questionnaires at 20 (New Zealand) or 26 (United Kingdom) years after index birth (n = 6195). Regression analyses investigated associations between risk factors and UI, FI and prolapse symptoms.

MAIN OUTCOME MEASURES

Prevalence of self-reported UI, FI, 'something coming down' from or in the vagina (SCD), and the Pelvic Organ Prolapse-Symptom Score, and relationships with delivery method.

RESULTS

Thirty-seven per cent (n = 2270) responded at 20/26 years, of whom 61% reported UI (59% of whom reported more severe UI), 22% FI and 17% prolapse symptoms. Having only caesarean section (CS) was associated with a significantly lower risk of UI (OR 0.63, 95% CI 0.46-0.85), FI (OR 0.63, 95% CI 0.42-0.96) and SCD (OR 0.44, 95% CI 0.27-0.74) compared to only spontaneous vaginal deliveries (SVDs). Having any forceps delivery was associated with reporting FI compared to only SVDs (OR 1.29, 95% CI 1.00-1.66), but there was no association for UI (OR 0.95, 95% CI 0.76-1.19) or SCD (OR 1.05, 95% CI 0.80-1.38). Higher current BMI was associated with all PFD outcomes.

CONCLUSIONS

Prevalence of PFD continues to increase up to 26 years following index birth, and differences were observed according to delivery mode history. Exclusive CS was associated with less risk of UI, FI and any prolapse symptoms.

摘要

目的

调查产后20年及以上的盆底功能障碍(PFD;尿失禁(UI)、粪失禁(FI)和脱垂)及其与分娩方式史和人口统计学特征的关联。

设计

长期随访队列研究。

地点

英国阿伯丁和伯明翰以及新西兰达尼丁的产科单位。

研究对象

1993/1994年分娩的女性。

方法

在索引分娩后20年(新西兰)或26年(英国)进行邮寄问卷调查(n = 6195)。回归分析调查了风险因素与UI、FI和脱垂症状之间的关联。

主要观察指标

自我报告的UI、FI、“阴道内有东西脱出”(SCD)的患病率,以及盆腔器官脱垂症状评分,以及与分娩方式的关系。

结果

20/26年时有37%(n = 2270)做出回应,其中61%报告有UI(其中59%报告有更严重的UI),22%报告有FI,17%报告有脱垂症状。与仅自然阴道分娩(SVD)相比,仅行剖宫产(CS)与UI(比值比[OR]0.63,95%置信区间[CI]0.46 - 0.85)、FI(OR 0.63,95% CI 0.42 - 0.96)和SCD(OR 0.44,95% CI 0.27 - 0.74)的风险显著降低相关。与仅SVD相比,有任何产钳助产史与报告有FI相关(OR 1.29,95% CI 1.00 - 1.66),但与UI(OR 0.95,95% CI 0.76 - 1.19)或SCD(OR 1.05,95% CI 0.80 - 1.38)无关。当前较高的体重指数(BMI)与所有PFD结局相关。

结论

索引分娩后26年内PFD患病率持续上升,且根据分娩方式史存在差异。单纯剖宫产与UI、FI及任何脱垂症状的风险较低相关。

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