肝脏对乙型肝炎病毒的免疫 - Suppr

Intrahepatic immunity to hepatitis B virus.

作者信息

Venzin Valentina, Beccaria Cristian G, Andreata Francesco, Fumagalli Valeria, Iannacone Matteo

机构信息

Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy.

Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy; Experimental Imaging Centre, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

出版信息

J Hepatol. 2024 Nov;81(5):911-913. doi: 10.1016/j.jhep.2024.05.029. Epub 2024 Jul 30.

DOI:10.1016/j.jhep.2024.05.029

PMID:39079776

Abstract

摘要

相似文献

Intrahepatic immunity to hepatitis B virus.肝脏对乙型肝炎病毒的免疫

J Hepatol. 2024 Nov;81(5):911-913. doi: 10.1016/j.jhep.2024.05.029. Epub 2024 Jul 30.

Diverse Virus and Host-Dependent Mechanisms Influence the Systemic and Intrahepatic Immune Responses in the Woodchuck Model of Hepatitis B.多种病毒和宿主依赖性机制影响土拨鼠乙型肝炎模型中的系统和肝内免疫反应。

Front Immunol. 2020 May 27;11:853. doi: 10.3389/fimmu.2020.00853. eCollection 2020.

Innate and adaptive immunity associated with resolution of acute woodchuck hepatitis virus infection in adult woodchucks.先天免疫和适应性免疫与成年土拨鼠急性 woodchuck 肝炎病毒感染的消退有关。

PLoS Pathog. 2019 Dec 23;15(12):e1008248. doi: 10.1371/journal.ppat.1008248. eCollection 2019 Dec.

[Quantitative detection of intrahepatic hepatitis B virus DNA in patients with chronic hepatitis B].慢性乙型肝炎患者肝内乙型肝炎病毒DNA的定量检测

Zhonghua Gan Zang Bing Za Zhi. 2003 Mar;11(3):173-5.

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.未治疗的慢性乙型肝炎患者肝内固有免疫反应途径下调。

J Hepatol. 2017 May;66(5):897-909. doi: 10.1016/j.jhep.2016.12.024. Epub 2016 Dec 30.

Single-cell landscape of functionally cured chronic hepatitis B patients reveals activation of innate and altered CD4-CTL-driven adaptive immunity.功能治愈的慢性乙型肝炎患者的单细胞景观揭示了固有免疫的激活和改变的 CD4-CTL 驱动的适应性免疫。

J Hepatol. 2024 Jul;81(1):42-61. doi: 10.1016/j.jhep.2024.02.017. Epub 2024 Feb 28.

Activation of intrahepatic CD4+CXCR5+ T and CD19+ B cells is associated with viral clearance in a mouse model of acute hepatitis B virus infection.在急性乙型肝炎病毒感染小鼠模型中，肝内CD4⁺CXCR5⁺ T细胞和CD19⁺ B细胞的激活与病毒清除有关。

Oncotarget. 2016 Aug 9;7(32):50952-50962. doi: 10.18632/oncotarget.10688.

Low hepatitis B virus-specific T-cell response in males correlates with high regulatory T-cell numbers in murine models.在小鼠模型中，男性乙型肝炎病毒特异性 T 细胞反应较低与调节性 T 细胞数量较高相关。

Hepatology. 2017 Jul;66(1):69-83. doi: 10.1002/hep.29155. Epub 2017 May 26.

HBeAg Is Indispensable for Inducing Liver Sinusoidal Endothelial Cell Activation by Hepatitis B Virus.HBeAg 对于乙型肝炎病毒诱导肝窦内皮细胞激活是不可或缺的。

Front Cell Infect Microbiol. 2022 Jan 31;12:797915. doi: 10.3389/fcimb.2022.797915. eCollection 2022.

Intrahepatic hepatitis B virus replication and liver histology in subjects with occult hepatitis B infection.隐匿性乙型肝炎感染患者的肝内乙型肝炎病毒复制和肝脏组织学。

Clin Microbiol Infect. 2016 Mar;22(3):290.e1-3. doi: 10.1016/j.cmi.2015.10.036. Epub 2015 Nov 14.

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CD4 T cells license Kupffer cells to reverse CD8 T cell dysfunction induced by hepatocellular priming.CD4 T细胞使库普弗细胞具备逆转由肝细胞致敏诱导的CD8 T细胞功能障碍的能力。

Nat Immunol. 2025 Jun 30. doi: 10.1038/s41590-025-02199-3.

High antigen burden drives CD8+ T cell dysfunction in a mouse model of chronic hepatitis B virus infection.在慢性乙型肝炎病毒感染小鼠模型中，高抗原负荷会导致CD8 + T细胞功能障碍。

J Virol. 2025 Jul 22;99(7):e0071125. doi: 10.1128/jvi.00711-25. Epub 2025 Jun 12.

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Intrahepatic immunity to hepatitis B virus.

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