Postgraduate Program of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
Postgraduate Program of Dentistry, Federal University of Santa Catarina, Florianópolis, Brazil.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2024 Oct;138(4):502-515. doi: 10.1016/j.oooo.2024.06.007. Epub 2024 Jun 19.
A systematic review was performed to synthesize and identify risk factors involved in TMD onset.
Electronic searches were conducted in PubMed, Web of Science, Scopus, Embase, PsyInfo and Lilacs databases, as well as in three gray literature databases (Google Scholar, ProQuest and Open grey). The studies were blindly assessed by two reviewers and selected by a pre-defined eligibility criterion. Risk of bias of included studies was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Cohort Studies. Grading of Recommendations Assessment, Development and Evaluation (GRADE) was evaluated for most related factors.
Twenty-one cohort studies were included. Significant factors were female gender, symptoms of depression and anxiety, perceived stress, sleep quality, symptoms of obstructive sleep apnea and presence of any comorbidity, such as Irritable Bowel Syndrome, lower back pain, headache frequency, tension-type headache, migraine and mixed headache. Moreover, high estrogen and low testosterone levels in utero, greater pain perception, jaw mobility pain, pain during palpation, orofacial anomalies, as well as extrinsic and intrinsic injuries were also significant.
Several factors seems to be involved in TMD onset, however, more studies with standardized methodology are necessary to confirm these findings.
系统评价旨在综合并确定颞下颌关节紊乱病发病的相关危险因素。
在 PubMed、Web of Science、Scopus、Embase、PsycINFO 和 Lilacs 数据库以及 3 个灰色文献数据库（Google Scholar、ProQuest 和 Open Grey）中进行电子检索。由两名评审员对研究进行盲法评估，并根据预先确定的合格标准进行选择。使用 Joanna Briggs 研究所队列研究批判性评估清单评估纳入研究的偏倚风险。针对最相关的因素进行推荐评估、制定和评估（GRADE）分级。
共纳入 21 项队列研究。显著的危险因素包括女性性别、抑郁和焦虑症状、感知压力、睡眠质量、阻塞性睡眠呼吸暂停症状和任何合并症的存在，如肠易激综合征、下腰痛、头痛频率、紧张性头痛、偏头痛和混合性头痛。此外，宫内高雌激素和低睾酮水平、更高的疼痛感知、下颌运动疼痛、触诊时疼痛、口面畸形以及外在和内在损伤也具有重要意义。
一些因素似乎与颞下颌关节紊乱病的发病有关，但需要更多采用标准化方法的研究来证实这些发现。
