Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, 7591538, Chile.
Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago, 7591538, Chile.
Hipertens Riesgo Vasc. 2024 Oct-Dec;41(4):240-250. doi: 10.1016/j.hipert.2024.07.001. Epub 2024 Jul 29.
This study aimed to examine the effects of a six-week of concurrent training using high-intensity interval plus resistance training on flow-mediated dilation and pulse wave velocity in hypertensive, elevated blood pressure, or normotensive. A secondary goal was to analyze the inter-individual variability.
A randomized controlled clinical trial was executed with 60 adult participants distributed across six groups: three control groups of hypertensive, elevated blood pressure, or normotensive and other three experimental hypertensive, elevated blood pressure, and normotensive groups, each comprising n=10 individuals. Participants underwent a six-week intervention of concurrent exercise using high-intensity interval plus resistance training three-weekly. Flow mediated dilation and pulse wave velocity and secondary vascular assessments were conducted before and after the intervention.
The hypertensive exercise group exhibited a significant increase in flow mediated dilation (Δ+7.7%; p=0.003) and a reduction in pulse wave velocity (Δ-1.2ms; p<0.0001). The normotensive exercise group also showed a significant increase in flow mediated dilation (Δ+8.4%, p=0.002).
The six-week concurrent exercise using high-intensity interval plus resistance training protocol, characterized by its clinical time-efficiency, was effective in improving endothelial function, as demonstrated by increased flow mediated dilation, and in reducing arterial stiffness, indicated by decreased pulse wave velocity.
本研究旨在探讨六周的高强度间歇加抗阻训练对高血压、血压升高或血压正常者的血流介导扩张和脉搏波速度的影响。次要目标是分析个体间的变异性。
一项随机对照临床试验在 60 名成年参与者中进行，参与者被分为六组：三组高血压、血压升高或血压正常的对照组和三组高血压、血压升高和血压正常的实验组，每组 10 人。参与者接受了为期六周的高强度间歇加抗阻训练的同期运动干预，每周三次。在干预前后进行血流介导扩张和脉搏波速度及次要血管评估。
高血压运动组血流介导扩张显著增加（Δ+7.7%；p=0.003），脉搏波速度降低（Δ-1.2ms；p<0.0001）。正常血压运动组血流介导扩张也显著增加（Δ+8.4%；p=0.002）。
六周的高强度间歇加抗阻训练同期运动方案，具有临床时间效率高的特点，可有效改善内皮功能，表现为血流介导扩张增加，降低动脉僵硬，脉搏波速度降低。
