• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Roux-en-Y 胃旁路术(RYGB)后迟发性食管裂孔疝(paraesophageal hernia,PEH)——是否需要修补?

Late-"de novo" paraesophageal hernia after Roux-en-Y gastric bypass (RYGB)-should it be repaired?

机构信息

Geisinger Health System, 100 North Academy Avenue, Danville, 17822, PA, USA.

Geisinger Commonwealth School of Medicine, 525 Pine Street, Scranton, 18509, PA, USA.

出版信息

Surg Endosc. 2024 Oct;38(10):5974-5979. doi: 10.1007/s00464-024-11083-4. Epub 2024 Jul 30.

DOI:10.1007/s00464-024-11083-4
PMID:39080062
Abstract

BACKGROUND

This study presents a case series of "de novo" paraesophageal hernia (dnPEH) in post-Roux-en-Y gastric bypass (RYGB) patients and analyzes the predisposing factors, symptoms, and outcomes after repair. This is a lesser known complication after RYGB and when symptomatic, may warrant surgery.

METHODS

A retrospective review of data from a single academic institution from 2002 to 2022 was performed identifying patients who developed dnPEH after RYGB and compared them to patients with primary RYGB without post-operative symptomatic dnPEH. Patient characteristics from initial RYGB were analyzed to identify predisposing factors for dnPEH development. Additional information analyzed included time to dnPEH repair, indications for surgery, types of herniation, type of surgical repair, and symptom resolution.

RESULTS

There were 6975 RYGB in the study period of which 6619 underwent RYGB alone at index surgery, with 31 of those patients developing late stage PEH requiring repair. Patients with older age (51.8 years with dnPEH vs 45.2 years without, p = 0.001) and increased weight loss at 1 year (33.4% vs 30.5%, p = 0.048) from index RYGB were more likely to develop dnPEH. The incidence of dnPEH was 31/6619 (0.47%). Late dnPEH after RYGB took an average of 74 months (45-102 months IQR) to develop symptoms and undergo repair. The most common symptoms were heartburn/reflux 19/31 (61.3%) and epigastric pain 13/31 (41.9%). Symptom resolution rate after repair was highest with 100% for globus and 89.5% heartburn/reflux. The most common form of dnPEH was pouch herniation in 25/31. Surgical repair most commonly included primary cruroplasty alone in 25/31 with additional mesh in 1 case. Recurrence rate was 2/31 (6.54%).

CONCLUSION

Late dnPEH after RYGB is an emerging entity typically occurring years after index RYGB. Symptomatic patients with dnPEH warrant hernia repair and responded well to surgical repair in this case series.

摘要

背景

本研究报告了 Roux-en-Y 胃旁路术(RYGB)后新发食管裂孔疝(dnPEH)的病例系列,并分析了其修复后的易患因素、症状和结果。这是 RYGB 术后不太常见的并发症,当出现症状时,可能需要手术治疗。

方法

对 2002 年至 2022 年期间单所学术机构的数据进行回顾性分析,确定在 RYGB 后发生 dnPEH 的患者,并将其与无术后症状性 dnPEH 的原发性 RYGB 患者进行比较。分析初始 RYGB 患者的特征,以确定 dnPEH 发生的易患因素。分析的其他信息包括 dnPEH 修复的时间、手术指征、疝类型、手术修复类型和症状缓解情况。

结果

在研究期间,共有 6975 例 RYGB,其中 6619 例在指数手术中仅行 RYGB,其中 31 例发生晚期 PEH 需要修复。年龄较大的患者(dnPEH 组 51.8 岁,无 dnPEH 组 45.2 岁,p=0.001)和 RYGB 后 1 年体重减轻较多的患者(dnPEH 组 33.4%,无 dnPEH 组 30.5%,p=0.048)更易发生 dnPEH。dnPEH 的发生率为 31/6619(0.47%)。RYGB 后晚期 dnPEH 出现症状并接受修复的平均时间为 74 个月(45-102 个月 IQR)。最常见的症状是烧心/反流 19/31(61.3%)和上腹痛 13/31(41.9%)。修复后的症状缓解率最高,球囊感为 100%,烧心/反流为 89.5%。最常见的 dnPEH 类型是袋疝,25/31 例。手术修复最常见的是单纯原发性横结肠成形术,25/31 例,1 例加用网片。复发率为 2/31(6.54%)。

结论

RYGB 后晚期 dnPEH 是一种新出现的实体,通常发生在 RYGB 指数后数年。有症状的 dnPEH 患者需要疝修复,在本病例系列中,手术修复效果良好。

相似文献

1
Late-"de novo" paraesophageal hernia after Roux-en-Y gastric bypass (RYGB)-should it be repaired?Roux-en-Y 胃旁路术(RYGB)后迟发性食管裂孔疝(paraesophageal hernia,PEH)——是否需要修补?
Surg Endosc. 2024 Oct;38(10):5974-5979. doi: 10.1007/s00464-024-11083-4. Epub 2024 Jul 30.
2
Concurrent hiatal hernia repair and gastric bypass as an adjunct in the treatment of hiatal hernia in populations with obesity.同期行食管裂孔疝修补术及胃旁路手术作为肥胖人群食管裂孔疝治疗的辅助手段。
Surg Endosc. 2025 Jun 16. doi: 10.1007/s00464-025-11854-7.
3
Subjective improvement of reflux symptoms after conversion of sleeve gastrectomy to Roux-en-Y gastric bypass and concomitant repair of hiatal hernia.胃袖状切除术转换为Roux-en-Y胃旁路术并同时修复食管裂孔疝后反流症状的主观改善
Surg Obes Relat Dis. 2025 Mar;21(3):256-262. doi: 10.1016/j.soard.2024.09.014. Epub 2024 Oct 9.
4
Paraesophageal hernia repair combined with Roux-en-Y gastric bypass reduces short-term hernia recurrence with added metabolic benefit in patients with BMI ≥ 35: A 15-year experience.食管旁疝修补术联合Roux-en-Y胃旁路术可降低BMI≥35患者的短期疝复发率,并带来额外的代谢益处:15年经验总结
Surg Endosc. 2025 Jun 26. doi: 10.1007/s00464-025-11950-8.
5
Paraesophageal hernia repair with concurrent bariatric surgery: a single institution experience on safety, benefit, and outcomes in obese patients.食管旁疝修补术联合减重手术:单机构对肥胖患者安全性、益处及结局的经验
Surg Endosc. 2025 Jul;39(7):4564-4575. doi: 10.1007/s00464-025-11812-3. Epub 2025 Jun 9.
6
Conversion of sleeve gastrectomy to Roux-en-Y gastric bypass: impact on reflux and weight loss.袖状胃切除术转为 Roux-en-Y 胃旁路术:对反流和减重的影响。
Surg Obes Relat Dis. 2024 Aug;20(8):738-744. doi: 10.1016/j.soard.2024.04.001. Epub 2024 Apr 6.
7
Closure of mesenteric defects for prevention of internal hernia after Roux-en-Y gastric bypass in bariatric surgery.肥胖症手术中Roux-en-Y胃旁路术后肠系膜缺损的闭合以预防内疝
Cochrane Database Syst Rev. 2025 Apr 8;4(4):CD014612. doi: 10.1002/14651858.CD014612.pub2.
8
Impact of post-RYGB gastrogastric fistula repair on metabolic and reflux outcomes.Roux-en-Y胃旁路术后胃胃瘘修复对代谢及反流结局的影响。
Surg Endosc. 2025 Jul 9. doi: 10.1007/s00464-025-11954-4.
9
Surgery for weight loss in adults.成人减肥手术。
Cochrane Database Syst Rev. 2014 Aug 8;2014(8):CD003641. doi: 10.1002/14651858.CD003641.pub4.
10
Efficacy and safety of single-anastomosis duodeno-ileal bypass with sleeve gastrectomy versus Roux-en-Y gastric bypass in France (SADISLEEVE): results of a randomised, open-label, superiority trial at 2 years of follow-up.法国单吻合十二指肠-回肠旁路术联合袖状胃切除术与Roux-en-Y胃旁路术的疗效和安全性比较(SADISLEEVE):一项随访2年的随机、开放标签、优效性试验结果
Lancet. 2025 Aug 23;406(10505):846-859. doi: 10.1016/S0140-6736(25)01070-0.

本文引用的文献

1
Hiatal hernia repair after previous laparoscopic Roux-en-Y gastric bypass.既往腹腔镜 Roux-en-Y 胃旁路术后的食管裂孔疝修补术
Surg Obes Relat Dis. 2024 May;20(5):432-437. doi: 10.1016/j.soard.2023.11.012. Epub 2023 Nov 25.
2
Incarcerated Diaphragmatic Hernias After Roux-en-Y Gastric Bypass.Roux-en-Y胃旁路术后的嵌顿性膈疝
Cureus. 2022 Dec 28;14(12):e33063. doi: 10.7759/cureus.33063. eCollection 2022 Dec.
3
Management of a Late-Term Hiatal Hernia with Intrathoracic Pouch Migration After Roux-en-Y Gastric Bypass.
Roux-en-Y胃旁路术后晚期食管裂孔疝伴胸腔内胃囊移位的处理
Obes Surg. 2022 Mar;32(3):957-958. doi: 10.1007/s11695-021-05881-1. Epub 2022 Jan 6.
4
Repair of post-bariatric surgery, recurrent, and de novo hiatal hernias improves bloating, abdominal pain, regurgitation, and food intolerance.减重手术后、复发性和新发的食管裂孔疝的修复可改善腹胀、腹痛、反流和食物不耐受。
Surg Obes Relat Dis. 2021 Apr;17(4):683-691. doi: 10.1016/j.soard.2020.12.006. Epub 2020 Dec 14.
5
Type IV Hiatal Hernia Containing the Gastric Pouch and Proximal Roux Limb: A Rare Cause of Bowel Obstruction Following Roux-en-Y Bypass Surgery.包含胃囊和近端Roux袢的IV型食管裂孔疝:Roux-en-Y旁路手术后肠梗阻的罕见原因。
Cureus. 2020 Aug 30;12(8):e10132. doi: 10.7759/cureus.10132.
6
Management of paraesophageal hernia review of clinical studies: timing to surgery, mesh use, fundoplication, gastropexy and other controversies.食管旁疝的管理:临床研究综述——手术时机、补片使用、胃底折叠术、胃固定术及其他争议
Dis Esophagus. 2020 Aug 3;33(8). doi: 10.1093/dote/doaa045.
7
Late-term hiatal hernia after gastric bypass: an emerging problem.胃旁路术后迟发性食管裂孔疝:一个新出现的问题。
Surg Obes Relat Dis. 2020 Apr;16(4):471-475. doi: 10.1016/j.soard.2020.01.018. Epub 2020 Jan 25.
8
Guidelines for the management of hiatal hernia.食管裂孔疝管理指南。
Surg Endosc. 2013 Dec;27(12):4409-28. doi: 10.1007/s00464-013-3173-3. Epub 2013 Sep 10.