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低出生体重早产儿肠内喂养充足性的前瞻性队列研究。

Enteral adequacy of the diet of low-birth-weight preterm newborns: A prospective cohort study.

机构信息

Postgraduate Program in Sciences Applied to Women's Health, Januário Cicco Maternity Teaching Hospital, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.

Januário Cicco Maternity Teaching Hospital (MEJC), Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.

出版信息

J Pediatr Gastroenterol Nutr. 2024 Sep;79(3):688-694. doi: 10.1002/jpn3.12340. Epub 2024 Jul 31.

Abstract

OBJECTIVE

This study aimed to verify the dietary adequacy of full enteral feeding in preterm newborns (PTNB) and its relationship with birth weight (BW) during the period of hospitalization in the neonatal intensive care unit (NICU).

METHODS

This is a prospective cohort study whose population were babies born at less than 37 gestational weeks and weighing less than 2500 g, admitted to a NICU. PTNB were monitored regarding their dietary evolution, considering parenteral and enteral nutrition and adequacy of diet supply in terms of volume, energy, and protein. For statistical analysis, the Statistical Package for the Social Sciences (SPSS) software was used, considering p < 0.05 as significant.

RESULTS

A total of 76 PTNB were included. The mean time of using parenteral nutrition was 14 days. The mean time to reach the full enteral feeding for nutrition (FEF-N) was 29 days. However, half of the PTNB reached nutritional recommendations after this means. The time to achieve FEF-N was influenced by BW. Additionally, BW significantly influenced the length of stay in the NICU (p < 0.001). When reaching the recommended full enteral feeding for hydration (FEF-H), 60% of the sample was unable to reach the recommended energy and protein intake.

CONCLUSIONS

BW influenced the time needed to reach the FEF-H and FEF-N. The lower the BW, the longer it took to achieve dietary adequacy. Despite achieving the FEF-H, most premature babies did not reach the necessary energy and protein intake at the appropriate time.

摘要

目的

本研究旨在验证早产儿(PTNB)全肠内喂养的饮食充足性及其与住院期间新生儿重症监护病房(NICU)内出生体重(BW)的关系。

方法

这是一项前瞻性队列研究,其研究人群为胎龄不足 37 周且体重不足 2500g 的婴儿,他们被收入 NICU。监测 PTNB 的饮食演变情况,考虑肠外和肠内营养以及饮食供应的体积、能量和蛋白质充足性。使用社会科学统计软件包(SPSS)进行统计分析,认为 p<0.05 具有统计学意义。

结果

共纳入 76 例 PTNB。使用肠外营养的平均时间为 14 天。达到完全肠内喂养营养(FEF-N)的平均时间为 29 天。然而,一半的 PTNB 在达到这一水平后才达到营养推荐量。达到 FEF-N 的时间受 BW 影响。此外,BW 显著影响 NICU 的住院时间(p<0.001)。当达到推荐的完全肠内喂养水合作用(FEF-H)时,60%的样本无法达到推荐的能量和蛋白质摄入。

结论

BW 影响达到 FEF-H 和 FEF-N 的时间。BW 越低,达到饮食充足所需的时间就越长。尽管达到了 FEF-H,但大多数早产儿没有在适当的时间达到必要的能量和蛋白质摄入。

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