Costanza Flavia, Cicia Martina, Giampietro Antonella, Tartaglione Tommaso, Angelini Flavia, Zoli Angelo, Ferrazzani Sergio, De Marinis Laura, Pontecorvi Alfredo, Bianchi Antonio, Chiloiro Sabrina
Department of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Department of Endocrinology, Diabetology and Internal Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Endocr Metab Immune Disord Drug Targets. 2024 Jul 30. doi: 10.2174/0118715303314953240719044233.
Hypophysitis is an inflammatory disorder of the pituitary gland. It can manifest variously, with endocrinological and neuro-ophthalmologic symptoms and signs, due to the compression of sellar and parasellar structures.
Although hypophysitis is rare, this pituitary disease can occur during pregnancy or in the postpartum period. In this report, we describe the case of a woman with partial hypopituitarism secondary to autoimmune hypophysitis who, five years after the diagnosis and the immunosuppressive treatment, had an uneventful pregnancy and successfully delivered a healthy infant at term.
We reported the clinical history of the patient and the evolution of the disease and also reviewed the management and treatment of autoimmune hypophysitis during pregnancy.
垂体炎是一种垂体的炎症性疾病。由于鞍区和鞍旁结构受压，它可表现出多种形式，伴有内分泌和神经眼科症状及体征。
尽管垂体炎罕见，但这种垂体疾病可发生在孕期或产后。在本报告中，我们描述了一名继发于自身免疫性垂体炎的部分垂体功能减退女性患者的病例，该患者在诊断及免疫抑制治疗五年后，孕期顺利并足月成功分娩一名健康婴儿。
我们报告了该患者的临床病史及疾病进展情况，并回顾了孕期自身免疫性垂体炎的管理与治疗。
