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评估患有化脓性汗腺炎患者的大麻相关产品使用情况:叙述性综述。

Evaluation of Cannabis-Related Product Use Among Patients With Hidradenitis Suppurativa: A Narrative Review.

机构信息

Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

J Cutan Med Surg. 2024 Sep-Oct;28(5):481-485. doi: 10.1177/12034754241266125. Epub 2024 Jul 31.

DOI:10.1177/12034754241266125
PMID:39082368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11528859/
Abstract

The use of cannabis and cannabis-related products among patients with hidradenitis suppurativa (HS) is increasing globally. Given the potential anti-inflammatory, therapeutic, and pain management benefits of cannabis-related products, we reviewed primary literature to evaluate the prevalence and possible purpose for cannabis use among patients with HS and to provide recommendations to patients and physicians. A narrative review of original studies was conducted using Embase and Ovid Medline databases. The search strategy was confirmed by a librarian and conducted on September 1, 2023, using a detailed list of subject headings and keywords tailored to cannabis, cannabis-related products, HS, and both adult and pediatric populations. Among 43 identified studies, 6 met the eligibility criteria and encompassed 34,435 patients. Patients were mostly female, and studies were conducted across the United States, Canada, and France. Findings show higher cannabis use among HS patients, demonstrating efficacy in pain management, sleep, anxiety relief, itch relief, and improved quality of life. Cannabis may play a role in analgesia, improved quality of life, pain, itch, and overall mental health in patients with HS and healthcare providers including dermatologists should increase their familiarity in appropriate use of cannabis-related products.

摘要

全球范围内,患有化脓性汗腺炎(HS)的患者对大麻和大麻类产品的使用正在增加。鉴于大麻类产品具有潜在的抗炎、治疗和疼痛管理益处,我们回顾了主要文献,以评估 HS 患者使用大麻的流行情况和可能的用途,并为患者和医生提供建议。我们使用 Embase 和 Ovid Medline 数据库对原始研究进行了叙述性综述。检索策略由一名图书管理员确认,并于 2023 年 9 月 1 日使用针对大麻、大麻类产品、HS 以及成人和儿科人群的详细主题词和关键字列表进行。在确定的 43 项研究中,有 6 项符合纳入标准,共纳入 34435 名患者。患者主要为女性,研究在美国、加拿大和法国进行。研究结果表明,HS 患者中大麻的使用率更高,在疼痛管理、睡眠、焦虑缓解、瘙痒缓解和生活质量改善方面显示出疗效。大麻可能在 HS 患者的镇痛、改善生活质量、疼痛、瘙痒和整体心理健康方面发挥作用,皮肤科医生等医疗保健提供者应提高对大麻类产品的适当使用的熟悉程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b37/11528859/a64d357b6a19/10.1177_12034754241266125-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b37/11528859/a64d357b6a19/10.1177_12034754241266125-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b37/11528859/a64d357b6a19/10.1177_12034754241266125-fig1.jpg

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J Cutan Med Surg. 2024 Sep-Oct;28(5):481-485. doi: 10.1177/12034754241266125. Epub 2024 Jul 31.
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本文引用的文献

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Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases.大麻素化合物作为治疗非癌症皮肤疾病的一种药物治疗选择。
Cells. 2022 Dec 16;11(24):4102. doi: 10.3390/cells11244102.
2
A Survey of Topical Cannabis Use in Canada.加拿大局部用大麻使用情况调查。
J Cutan Med Surg. 2022 Mar-Apr;26(2):156-161. doi: 10.1177/12034754211059025. Epub 2021 Nov 19.
3
Evaluating provider knowledge, perception, and concerns about cannabinoid use in pediatric dermatology.评估提供者在儿科皮肤病学中对大麻素使用的知识、看法和担忧。
Pediatr Dermatol. 2021 May;38(3):694-696. doi: 10.1111/pde.14539. Epub 2021 Mar 18.
4
Expert Knowledge, Attitudes, and Practices in Management of Hidradenitis Suppurativa Pain.专家对化脓性汗腺炎疼痛管理的知识、态度和实践。
JAMA Dermatol. 2021 Apr 1;157(4):464-466. doi: 10.1001/jamadermatol.2020.5857.
5
Pain management modalities for hidradenitis suppurativa: a patient survey.化脓性汗腺炎的疼痛管理方式:一项患者调查。
J Dermatolog Treat. 2022 May;33(3):1742-1745. doi: 10.1080/09546634.2020.1822501. Epub 2020 Sep 20.
6
Complementary and Alternative Medicine Use in Patients With Hidradenitis Suppurativa.化脓性汗腺炎患者中补充和替代医学的使用。
JAMA Dermatol. 2020 Mar 1;156(3):345-348. doi: 10.1001/jamadermatol.2019.4595.
7
Cannabidiol Adverse Effects and Toxicity.大麻二酚的不良反应和毒性。
Curr Neuropharmacol. 2019;17(10):974-989. doi: 10.2174/1570159X17666190603171901.
8
High prevalence of cannabis use among patients with hidradenitis suppurativa: results from the VERADDICT survey.化脓性汗腺炎患者中大麻使用的高流行率:VERADDICT调查结果
Br J Dermatol. 2019 Oct;181(4):839-841. doi: 10.1111/bjd.17930. Epub 2019 Jun 26.
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Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.化脓性汗腺炎:将炎症途径整合到一个连贯的致病模型中的系统评价。
Front Immunol. 2018 Dec 14;9:2965. doi: 10.3389/fimmu.2018.02965. eCollection 2018.
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Knowledge, Attitudes, and Perceptions of Cannabinoids in the Dermatology Community.皮肤科领域对大麻素的认知、态度和看法
J Drugs Dermatol. 2018 Dec 1;17(12):1273-1278.