Mishra Gitanjali, Yazhinimuthu C M, Thirupathi Barla
Department of Chemical Sciences, Indian Institute of Science Education and Research Berhampur, Transit Campus, Govt. ITI Building, NH 59, Engineering School Road, Ganjam-District, Berhampur, 760 010, Odisha, India.
Chem Asian J. 2024 Oct 16;19(20):e202400667. doi: 10.1002/asia.202400667. Epub 2024 Sep 24.
Synthesis of functionalized 1,3-indandiones containing-cyclopentenones and -benzotropones has been achieved by the reaction of 1,5-diphenylpenta-1,4-diyn-3-ones with 1,3-indandiones, bindone respectively. The developed method involves Michael-anti-Michael addition cascade reactions under transition-metal-free conditions. This is the first report to synthesise diverse benzotropone fused with 1,3-indandiones under transition metal-free conditions from bindone.
通过1,5-二苯基戊-1,4-二炔-3-酮分别与1,3-茚二酮、苯偶姻酮反应，实现了含环戊烯酮和苯并环庚三烯酮的功能化1,3-茚二酮的合成。所开发的方法涉及无过渡金属条件下的迈克尔-反迈克尔加成串联反应。这是首次在无过渡金属条件下从苯偶姻酮合成与1,3-茚二酮稠合的多种苯并环庚三烯酮的报道。
