Departments of Medicine, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Department of Medicine, University College Hospital, Ibadan, Oyo State, Nigeria.
Niger J Clin Pract. 2024 Jul 1;27(7):873-879. doi: 10.4103/njcp.njcp_55_24. Epub 2024 Jul 27.
The outlook of chronic kidney disease (CKD) in low-and-medium-income-countries is poor. Modern farming practices in Nigeria are becoming increasingly associated with the use of herbicides and pesticides.
The study aimed to evaluate agrochemical use in farming practices and risk factors for kidney disease among dwellers of rural farming communities in South-West Nigeria.
This was a cross-sectional survey of adult dwellers of an agrarian rural farming community in South-West Nigeria. Participants provided information on demographics, lifestyles, knowledge, and awareness of risk factors for kidney disease, and the use of agrochemicals in farming practice. Anthropometric measurements and blood pressure values were obtained while blood and spot urine were collected for random blood glucose, serum creatinine, urinalysis, and albumin-creatinine ratio.
A total of 572 rural dwellers were enrolled in the study, with a mean age of 49.9 ± 17.5 years while 39.3% were male and 88.9% engaged in active farming. The prevalence of traditional risk factors for kidney disease was hypertension (24.3%), Diabetes mellitus (2.8%), cigarette smoking (7.5%), alcohol intake (20.8%) and herbal consumption (57.1%). The use of pesticides/herbicides was reported in 69.9%, while 25.3% did not use protective gear during its use. Proteinuria, hematuria, and reduced eGFR were observed in 29.8%, 6.1%, and 33.9% of participants, respectively.
This study showed a high prevalence of herbicides and pesticide use and traditional risk factors for kidney disease, in addition to the high prevalence of markers of kidney damage among the dwellers of rural farming settlements in South-West Nigeria.
在中低收入国家，慢性肾脏病（CKD）的前景不容乐观。尼日利亚的现代农业实践越来越多地与除草剂和农药的使用相关联。
本研究旨在评估尼日利亚西南部农村农业社区居民农业实践中农用化学品的使用情况以及肾脏病的危险因素。
这是对尼日利亚西南部一个农业农村社区的成年居民进行的横断面调查。参与者提供了有关人口统计学、生活方式、肾脏病危险因素的知识和意识以及农业实践中农用化学品使用情况的信息。测量了人体测量学指标和血压值，并采集了血液和随机尿液样本，用于检测随机血糖、血清肌酐、尿液分析和白蛋白-肌酐比。
共有 572 名农村居民参加了这项研究，平均年龄为 49.9±17.5 岁，其中 39.3%为男性，88.9%从事积极的农业劳动。肾脏病的传统危险因素包括高血压（24.3%）、糖尿病（2.8%）、吸烟（7.5%）、饮酒（20.8%）和草药摄入（57.1%）。报告使用了杀虫剂/除草剂的占 69.9%，而 25.3%的人在使用时没有使用防护装备。蛋白尿、血尿和 eGFR 降低分别在 29.8%、6.1%和 33.9%的参与者中观察到。
本研究表明，在尼日利亚西南部农村农业定居点的居民中，除草剂和农药的使用以及肾脏病的传统危险因素的流行率很高，此外，肾脏损伤的标志物的流行率也很高。
