Friedman E A, Chou L M, Beyer M M, Butt K M, Manis T
Hypertension. 1985 Nov-Dec;7(6 Pt 2):II131-4. doi: 10.1161/01.hyp.7.6_pt_2.ii131.
The effect of hypertension on patient and allograft survival in 60 diabetic recipients of transplanted kidneys was assessed by retrospective chart analysis. Hypertension was present in 81% of recipients. Of eight of these patients who became normotensive after transplantation, all had functioning allografts and one died. By contrast, persistent hypertension after transplantation was associated with a higher mortality rate (25 of 54, 48%) and loss of kidney graft function (19 of 54, 35%). At a mean of 21 months after transplantation, living hypertensive diabetic recipients had worse renal function (mean serum creatinine of 3.1 mg/dl) than did nonhypertensive recipients (mean serum creatinine of 1.6 mg/dl). It is concluded that hypertension is a significant risk factor for diabetic patients and kidneys after transplantation.
通过回顾性图表分析评估了高血压对60例糖尿病肾移植受者患者及移植肾存活的影响。81%的受者存在高血压。在移植后血压恢复正常的8例患者中，所有移植肾均功能良好，1例死亡。相比之下，移植后持续性高血压与较高的死亡率（54例中有25例，48%）及移植肾功能丧失（54例中有19例，35%）相关。移植后平均21个月时，仍患有高血压的糖尿病受者肾功能（平均血清肌酐为3.1mg/dl）比血压正常的受者（平均血清肌酐为1.6mg/dl）更差。得出的结论是，高血压是糖尿病患者及移植后肾脏的一个重要危险因素。
