Schwinn Tamara, Hirschmiller Judith, Brähler Elmar, Merzenich Hiltrud, Faber Jörg, Wild Philipp S, Beutel Manfred E, Ernst Mareike
Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Integrated Research and Treatment Center Adiposity Diseases, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.
J Psychosoc Oncol. 2025;43(2):230-247. doi: 10.1080/07347332.2024.2379827. Epub 2024 Jul 31.
Cancer survivors are at risk for suicidality. We aimed to expand the knowledge about protective factors and their interplay with risk factors by testing social support as a modifier of the association of Quality of Life (QoL) deficits with suicidal ideation.
We surveyed = 633 childhood cancer survivors (CCS) using validated questionnaires (EORTC Core Quality of Life questionnaire QLQ-C30, Patient Health Questionnaire PHQ-9). The interaction of QoL and social support was investigated using multiple linear regression analysis.
CCS reporting suicide attempts and current suicidal ideation (SI) had lower QoL. CCS with SI reported less social support. QoL and social support were independently associated with SI and interacted: among CCS with less social support, low QoL was more strongly associated with SI.
The results highlight the need for interdisciplinary survivorship care, and to focus on risk and protective factors to strengthen suicide prevention.
癌症幸存者存在自杀风险。我们旨在通过测试社会支持作为生活质量（QoL）缺陷与自杀意念之间关联的调节因素，来扩展对保护因素及其与风险因素相互作用的认识。
我们使用经过验证的问卷（欧洲癌症研究与治疗组织核心生活质量问卷QLQ-C30、患者健康问卷PHQ-9）对633名儿童癌症幸存者（CCS）进行了调查。使用多元线性回归分析研究生活质量和社会支持的相互作用。
报告有自杀未遂和当前自杀意念（SI）的CCS生活质量较低。有SI的CCS报告的社会支持较少。生活质量和社会支持与SI独立相关且相互作用：在社会支持较少的CCS中，低生活质量与SI的关联更强。
结果强调了跨学科生存护理的必要性，并需关注风险和保护因素以加强自杀预防。
