与大量抗肾小球和抗肾小管基底膜沉积物相关的排斥反应相关肾病综合征。
Rejection-related nephrotic syndrome associated with massive antiglomerular and antitubular basement membrane deposits.
作者信息
Zevin D, Ben-Bassat M, Weinstein T, Shapira Z, Levi J
出版信息
Isr J Med Sci. 1985 Nov;21(11):915-8.
PMID:3908399
Abstract
A patient with end-stage renal disease due to nephronophthisis developed nephrotic syndrome following renal transplantation. Renal biopsy revealed rejection glomerulopathy with massive linear deposition of immunoglobulin (Ig) G and complement C3 along the glomerular and tubular basement membranes. The association of nephrotic syndrome with linear deposition of Ig is rare in chronic rejection of kidney allografts. The nephrotic syndrome in this case responded to treatment with plasmapheresis.
摘要
一名因肾单位肾痨导致终末期肾病的患者在肾移植后出现肾病综合征。肾活检显示排斥性肾小球病，免疫球蛋白（Ig）G和补体C3沿肾小球和肾小管基底膜呈大量线性沉积。在同种异体肾移植慢性排斥反应中，肾病综合征与Ig线性沉积相关的情况较为罕见。该病例中的肾病综合征经血浆置换治疗后有反应。
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