Goeken N E
Hum Immunol. 1985 Oct;14(2):77-85. doi: 10.1016/0198-8859(85)90066-7.
Analysis of retrospective data, obtained on 216 patients from 27 centers transplanted across some form of positive lymphocyte cross-match in a noncurrent serum, revealed that actuarial 1-yr graft survival was 69% in first transplants and 53% in recipients of second or subsequent transplants. Graft outcome did not correlate with peak antibody levels, change in antibody from peak to current, remoteness in time of the most recent positive serum, the number or timing of sera cross-matched, the technique or target cell cross-matched, or the degree of positivity of the most recent positive serum. Although a concurrent control population was not available, these results support the concept that acceptable graft survival can be achieved despite a positive cross-match with noncurrent sera.
对来自27个中心的216例患者的回顾性数据进行分析，这些患者在非当前血清中进行了某种形式的阳性淋巴细胞交叉配型移植，结果显示，首次移植的1年实际移植物存活率为69%，第二次或后续移植受者的存活率为53%。移植物结果与峰值抗体水平、抗体从峰值到当前的变化、最近一次阳性血清的时间间隔、交叉配型血清的数量或时间、交叉配型的技术或靶细胞，或最近一次阳性血清的阳性程度均无相关性。尽管没有同期对照人群，但这些结果支持这样一种概念，即尽管与非当前血清交叉配型呈阳性，但仍可实现可接受的移植物存活率。
