Bocanegra-Becerra Jhon E, Acha Sánchez José Luis
Academic Department of Surgery, School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
Vascular Neurosurgery and Skull Base Division, Department of Neurosurgery, Hospital Nacional Dos de Mayo, Lima, Peru.
World Neurosurg. 2024 Nov;191:35-36. doi: 10.1016/j.wneu.2024.07.159. Epub 2024 Jul 30.
Basilar apex aneurysms (BAAs) represent 5%-8% of cerebral aneurysms. Treating BAAs is long established in neurosurgery. The morbid and lethal characteristics of aneurysmal subarachnoid hemorrhage coupled with potential medical complications of neurointensive care contribute to poor prognosis of patients with ruptured BAAs. A 58-year-old woman presented to the emergency department with a 1-day course of intense headaches that progressed to loss of consciousness. Noncontrast computed tomography of the head revealed extensive intraventricular hemorrhage (Fisher grade 4). Computed tomography angiography revealed an 8.7 × 6.3 mm wide-neck BAA. Preoperatively, she developed rebleeding and cerebral vasospasm and was transferred to the neurointensive care unit. After initial management and consideration of her clinical course and complex aneurysm features, she underwent a right frontotemporal craniotomy and anterior extradural clinoidectomy to perform aneurysm neck clipping (Video 1). Endovascular treatment was not considered, given that our facility belongs to a low-income public health system with limited availability of endovascular devices. Postoperatively, the patient developed cerebral vasospasm and pneumonia, which led to respiratory failure and death. BAAs are vascular entities that require arduous microsurgical treatment. Despite the increasing trend in managing these patients with endovascular treatment, the role of microsurgery is predominant in clinical settings with limited availability of alternative therapies. This clinical scenario requires neurosurgery trainees to achieve a high-level microsurgical skill set to provide optimal treatment. Nonetheless, the course of BAAs can still be poor even after adequate surgical management. This case exemplifies the burdensome nature of BAAs and the difficult clinical course of patients despite meticulous microsurgical management. Fisher grade 4, which is associated with a 31% risk of vasospasm, was a notable factor contributing to this outcome. Further, the patient's recovery was complicated by hospital-acquired pneumonia, which has a mortality rate of 9.7%. Accordingly, amid the emergent discipline of enhanced recovery after surgery, optimized protocols for postoperative management could benefit these patients..
基底动脉尖部动脉瘤(BAA)占脑动脉瘤的5%-8%。神经外科治疗BAA已有很长时间。动脉瘤性蛛网膜下腔出血的致病和致死特性,再加上神经重症监护的潜在医疗并发症,导致破裂BAA患者的预后较差。一名58岁女性因剧烈头痛1天就诊于急诊科,后发展为意识丧失。头颅非增强计算机断层扫描显示广泛的脑室内出血(Fisher分级4级)。计算机断层扫描血管造影显示一个8.7×6.3毫米的宽颈BAA。术前,她发生了再出血和脑血管痉挛,并被转入神经重症监护病房。在进行初步处理并考虑她的临床病程和复杂的动脉瘤特征后,她接受了右额颞开颅术和前硬膜外眶内切除术以进行动脉瘤夹闭(视频1)。由于我们的机构属于低收入公共卫生系统,血管内装置供应有限,因此未考虑血管内治疗。术后,患者发生了脑血管痉挛和肺炎,导致呼吸衰竭和死亡。BAA是需要艰苦显微外科治疗的血管病变。尽管使用血管内治疗管理这些患者的趋势在增加,但在替代疗法可用性有限的临床环境中,显微外科的作用仍然占主导地位。这种临床情况要求神经外科实习生具备高水平的显微外科技能,以提供最佳治疗。尽管如此,即使经过充分的手术治疗,BAA的病程仍可能较差。这个病例体现了BAA的沉重性质以及尽管进行了细致的显微外科管理,患者的临床病程仍很艰难。与31%的血管痉挛风险相关的Fisher分级4级是导致这一结果的一个显著因素。此外,患者的康复因医院获得性肺炎而复杂化,医院获得性肺炎的死亡率为9.7%。因此,在新兴的术后加速康复学科中,优化的术后管理方案可能会使这些患者受益。