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布鲁氏菌作为严重脓毒症的病因:病例系列及简要综述

Brucella as a cause of severe sepsis: Case series and brief review.

作者信息

Deng Linlin, Yu Jiazhen, Li Hongyan, Zhang Hong

机构信息

Department of Clinical Laboratory, Nanchong Central Hospital, Sichuan, China.

Department of Clinical Laboratory, Nanchong Central Hospital, Sichuan, China.

出版信息

Am J Med Sci. 2025 Jan;369(1):116-121. doi: 10.1016/j.amjms.2024.07.032. Epub 2024 Jul 30.

Abstract

Brucellosis is a serious public health problem worldwide and can affect any organ system. Due to brucellosis's variable clinical presentation, ranging from subclinical to fully symptomatic, and limited available information, it poses a diagnostic challenge. In this study, we reported a case series of patients with diverse presentations. In addition, we briefly described the pathophysiology and mechanisms of Brucella in the body. These case presentations will be valuable in increasing the awareness of physicians. A prompt diagnosis is crucial, as detecting some clues of the infection in its early stages can help avoid misdiagnoses.

摘要

布鲁氏菌病是全球范围内一个严重的公共卫生问题,可影响任何器官系统。由于布鲁氏菌病的临床表现多样,从亚临床到完全有症状,且可用信息有限,因此它构成了诊断挑战。在本研究中,我们报告了一系列表现各异的患者病例。此外,我们简要描述了布鲁氏菌在体内的病理生理学和机制。这些病例报告对于提高医生的认识将具有重要价值。及时诊断至关重要,因为在感染早期发现一些感染线索有助于避免误诊。

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