Retief D H, Harris B E, Bradley E L, Denys F R
J Biomed Mater Res. 1985 Mar;19(3):335-48. doi: 10.1002/jbm.820190314.
The objective of this study was to evaluate the use of pyruvic acid as an alternative etching agent to phosphoric acid (H3PO4). Solutions containing 5, 10, 15, 20, 25, and 30 m/m % pyruvic acid and 50% m/m H3PO4 were prepared. The tensile bond strengths of a composite resin to enamel surfaces etched with the respective etching agents were determined. The rates of etching of enamel surfaces by each of the etching solutions were evaluated. Unground and polished enamel surfaces were etched with the respective etching solutions and the surfaces examined by scanning electron microscopy. The tensile bond strengths of the resin to enamel surfaces etched with 10-30% pyruvic acid exceeded those obtained on enamel surfaces etched with 50% H3PO4. The rates of etching of all the pyruvic acid solutions were significantly less than of H3PO4. Well-defined etching patterns were observed on the enamel surfaces etched with all the etching solutions. The results of this laboratory study suggest that pyruvic acid may be a suitable alternative to phosphoric acid as an etching agent in clinical dentistry.
本研究的目的是评估丙酮酸作为磷酸（H3PO4）替代蚀刻剂的用途。制备了含有5%、10%、15%、20%、25%和30%质量/质量百分比丙酮酸以及50%质量/质量百分比H3PO4的溶液。测定了复合树脂与用相应蚀刻剂蚀刻的牙釉质表面之间的拉伸粘结强度。评估了每种蚀刻溶液对牙釉质表面的蚀刻速率。用相应的蚀刻溶液蚀刻未打磨和抛光的牙釉质表面，并通过扫描电子显微镜检查这些表面。用10% - 30%丙酮酸蚀刻的牙釉质表面上树脂的拉伸粘结强度超过了用50% H3PO4蚀刻的牙釉质表面上的粘结强度。所有丙酮酸溶液的蚀刻速率均显著低于H3PO4的蚀刻速率。在用所有蚀刻溶液蚀刻的牙釉质表面上均观察到了清晰的蚀刻图案。这项实验室研究的结果表明，在临床牙科中，丙酮酸可能是一种适合替代磷酸的蚀刻剂。
