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全膝关节置换术采用骨水泥固定的单半径、髁间稳定设计,不牺牲后交叉韧带。

Total knee arthroplasty using a cemented single-radius, condylar-stabilized design performed without posterior cruciate ligament sacrifice.

机构信息

Department of Orthopaedics, Golden Jubilee University National Hospital, Clydebank, UK.

School of Medicine, University of St Andrews, St Andrews, UK.

出版信息

Bone Joint J. 2024 Aug 1;106-B(8):808-816. doi: 10.1302/0301-620X.106B8.BJJ-2023-1371.R1.

Abstract

AIMS

Total knee arthroplasty (TKA) with a highly congruent condylar-stabilized (CS) articulation may be advantageous due to increased stability versus cruciate-retaining (CR) designs, while mitigating the limitations of a posterior-stabilized construct. The aim was to assess ten-year implant survival and functional outcomes of a cemented single-radius TKA with a CS insert, performed without posterior cruciate ligament sacrifice.

METHODS

This retrospective cohort study included consecutive patients undergoing TKA at a specialist centre in the UK between November 2010 and December 2012. Data were collected using a bespoke electronic database and cross-referenced with national arthroplasty audit data, with variables including: preoperative characteristics, intraoperative factors, complications, and mortality status. Patient-reported outcome measures (PROMs) were collected by a specialist research team at ten years post-surgery. There were 536 TKAs, of which 308/536 (57.5%) were in female patients. The mean age was 69.0 years (95% CI 45.0 to 88.0), the mean BMI was 32.2 kg/m (95% CI 18.9 to 50.2), and 387/536 (72.2%) survived to ten years. There were four revisions (0.7%): two deep infections (requiring debridement and implant retention), one aseptic loosening, and one haemosiderosis.

RESULTS

Kaplan-Meier analysis demonstrated no difference in implant survival according to sex, age, or obesity status. Ten-year PROMs were available for 196/387 (50.6%) surviving patients and were excellent: mean Oxford Knee Score 34.4 (95% CI 32.7 to 36.1); mean Forgotten Joint Score (FJS) 51.2 (95% CI 16.1 to 86.3); mean EuroQol five-dimension five-level questionnaire score 69.9 (95% CI 46.8 to 93.0); 141/196 (71.9%) achieved the 22-point FJS patient-acceptable symptom state (PASS); and 156/196 (79.6%) were "very satisfied or satisfied".

CONCLUSION

This is the only large study reporting ten-year implant survival and functional outcomes of TKA using a cemented single-radius design and with a CS tibial bearing construct. The findings of excellent implant survival, safety, and functional outcomes indicate that this combination is a safe and effective option in routine TKA. Further investigation of this single-radius design TKA with CS tibial bearings with well-matched patient study groups will allow further insight into the performance of these implants.

摘要

目的

与保留交叉韧带(CR)设计相比,具有高度一致的髁间稳定(CS)关节的全膝关节置换术(TKA)可能具有增加的稳定性,同时减轻了后稳定结构的局限性。目的是评估在不牺牲后交叉韧带的情况下,使用 CS 插入物进行的具有 CS 插入物的骨水泥单半径 TKA 的十年植入物存活率和功能结果。

方法

这是一项回顾性队列研究,纳入了 2010 年 11 月至 2012 年 12 月期间在英国一家专科中心接受 TKA 的连续患者。使用定制的电子数据库收集数据,并与国家关节置换术审计数据进行交叉参考,变量包括:术前特征、术中因素、并发症和死亡率。手术后十年,由专业研究团队收集患者报告的结果测量(PROM)。共有 536 例 TKA,其中 308/536(57.5%)为女性患者。平均年龄为 69.0 岁(95%CI 45.0 至 88.0),平均 BMI 为 32.2kg/m(95%CI 18.9 至 50.2),387/536(72.2%)存活至十年。有 4 例(0.7%)修订:2 例深部感染(需要清创和保留植入物),1 例无菌性松动,1 例含铁血黄素沉着症。

结果

Kaplan-Meier 分析表明,植入物存活率与性别、年龄或肥胖状况无关。在幸存的 196/387(50.6%)名患者中,可获得十年的 PROM,并表现出色:平均牛津膝关节评分 34.4(95%CI 32.7 至 36.1);平均遗忘关节评分(FJS)51.2(95%CI 16.1 至 86.3);平均欧洲五维健康量表五分问卷评分 69.9(95%CI 46.8 至 93.0);141/196(71.9%)达到 22 分 FJS 患者可接受症状状态(PASS);和 156/196(79.6%)“非常满意或满意”。

结论

这是唯一一项报告使用骨水泥单半径设计和 CS 胫骨轴承结构的 TKA 的十年植入物存活率和功能结果的大型研究。出色的植入物存活率、安全性和功能结果表明,这种组合是常规 TKA 的一种安全有效的选择。对具有 CS 胫骨轴承的这种单半径设计 TKA 进行进一步研究,并与匹配良好的患者研究组进行比较,可以进一步了解这些植入物的性能。

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