Division of Cardiology, Rush University Medical Center, 1717 West Congress Parkway, Chicago, IL 60612, USA.
Department of Cardiology, Yeditepe University Hospital, Istanbul 34100, Turkey.
Card Electrophysiol Clin. 2024 Sep;16(3):297-305. doi: 10.1016/j.ccep.2023.12.005. Epub 2024 Jan 12.
Catheter-based neuromodulation of intrinsic cardiac autonomic nervous system is increasingly being used to improve outcomes in patients with vasovagal syncope and bradyarrhythmias caused by vagal overactivity. However, there is still no consensus for patient selection, technical steps, and procedural end points. This review takes the reader on a practical exploration of neuromodulation for bradyarrhythmias, concentrating on the critical aspects of proper patient selection, evidence-based insights, and anatomic intricacies within the intrinsic cardiac autonomic nervous system. Also discussed are different mapping techniques and outcome measures. Future directions to optimize the utilization of this technique in clinical practice are highlighted.
经导管心脏自主神经系统内神经调节技术越来越多地用于改善血管迷走性晕厥和迷走神经活性过高引起的缓慢性心律失常患者的预后。然而,目前仍然没有关于患者选择、技术步骤和程序终点的共识。本综述将引导读者深入了解心脏自主神经系统内神经调节技术在缓慢性心律失常中的应用,重点介绍正确的患者选择、基于证据的见解以及心脏自主神经系统内解剖复杂性等关键方面。此外,还讨论了不同的映射技术和结果衡量指标。强调了优化该技术在临床实践中应用的未来方向。