Department of Medicine IV, Institute for Endocrinology, Diabetology & Metabolism, Klinikum der Universität München, Ziemssenstraße 1, München 80336, Germany.
Department of Pharmacology, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, MSRB II, 5560A, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA; Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan, MSRB II, 5560A, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA.
Endocrinol Metab Clin North Am. 2024 Sep;53(3):391-407. doi: 10.1016/j.ecl.2024.05.005. Epub 2024 Jun 25.
Over the last several decades, children with all forms of classic congenital adrenal hyperplasia (CAH) are identified early and treated appropriately throughout childhood. As adults, women with CAH may desire to become mothers and their usual chronic therapy and disease control is often inadequate for conception. Subsequently, little data exist on their management during pregnancy. Pregnancy in women with various forms of CAH is possible with appropriate treatment. Achieving pregnancy is more complex than disease management during pregnancy.
在过去几十年中，患有各种经典先天性肾上腺皮质增生症 (CAH) 的儿童都能被早期发现并在整个儿童期得到适当治疗。作为成年人，患有 CAH 的女性可能希望成为母亲，但她们通常的慢性治疗和疾病控制往往不足以实现受孕。因此，关于她们在怀孕期间的管理的数据很少。各种形式的 CAH 女性是可以怀孕的，只要接受适当的治疗。实现怀孕比在怀孕期间管理疾病要复杂得多。
