Department of Psychology, Temple University, Philadelphia, Pennsylvania 19122, USA
Department of Psychology, Temple University, Philadelphia, Pennsylvania 19122, USA.
Learn Mem. 2024 Jul 31;31(7). doi: 10.1101/lm.053869.123. Print 2024 Jul.
Incubation of craving is a phenomenon describing the intensification of craving for a reward over extended periods of abstinence from reinforcement. Animal models use instrumental markers of craving to reward cues to examine incubation, while human paradigms rely on subjective self-reports. Here, we characterize an animal-inspired, novel human paradigm that showed strong positive relationships between self-reports and instrumental markers of craving for favored palatable foods. Further, we found consistent nonlinear relationships with time since last consumption and self-reports, and preliminary patterns between time and instrumental responses. These findings provide a novel approach to establishing an animal-inspired human model of incubation.
渴望孵育是一种现象，描述了在长时间戒除强化物后对奖励的渴望的增强。动物模型使用工具性的渴望标记物来奖励线索，以检查孵育过程，而人类范式则依赖于主观的自我报告。在这里，我们描述了一种受动物启发的新颖的人类范式，该范式显示了对喜爱的美味食物的自我报告和工具性渴望标记物之间的强烈正相关关系。此外，我们发现与上次消费后的时间和自我报告之间存在一致的非线性关系，以及时间和工具性反应之间的初步模式。这些发现为建立受动物启发的人类孵育模型提供了一种新方法。
