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利用吐温 80 和卵磷脂的复杂界面结构的纳米结构来调节脂类消化。

Modulation of Lipid Digestion by Nanoarchitectonics of Complex Interfacial Structures with Tween 80 and Lecithin.

机构信息

Key Laboratory of Geriatric Nutrition and Health, Beijing Technology and Business University.

School of Light Industry, Beijing Technology and Business University.

出版信息

J Oleo Sci. 2024;73(8):1125-1134. doi: 10.5650/jos.ess24097.

DOI:10.5650/jos.ess24097
PMID:39085085
Abstract

In recent years, there has been a growing interest in regulating lipid digestion through the construction of various interfacial structures. In the present work, a series of complex interfacial structures were designed by combining Tween 80 in the aqueous phase and lecithin in the oil phase at different concentration ratios. The emulsification properties, the roles in regulating lipid digestion, and the interfacial dilatational rheological properties of the composite emulsifying systems were characterized. The results showed that the combination of Tween 80 and lecithin at different ratios could effectively modulate the rate of lipid digestion. The polyoxyethylene chains of Tween 80 formed a network, that provided a spatial obstacle for the adsorption of bile salts and lipases. Thus, Tween 80 significantly delayed the lipid digestion. The introduction of lecithin gradually replaced Tween 80 molecules at the interface, thus providing space for the adsorption of bile salts and lipases. In addition, as the ratio of lecithin concentration to Tween 80 increased, lecithin gradually became the dominant factor in the interfacial properties. As a result, the rate of lipid digestion was accelerated. Therefore, by compounding different ratios of lecithin and Tween 80, a series of emulsions with different lipid digestion rates were obtained. This research provides a basis for rationally designing food emulsions according to specific needs.

摘要

近年来,人们对通过构建各种界面结构来调节脂质消化产生了越来越大的兴趣。在本工作中,通过在水相和油相中将吐温 80 和卵磷脂以不同的浓度比组合,设计了一系列复杂的界面结构。对复合乳化体系的乳化性能、调节脂质消化的作用以及界面扩张流变性能进行了表征。结果表明,吐温 80 和卵磷脂以不同比例的组合可以有效地调节脂质消化的速率。吐温 80 的聚氧乙烯链形成网络,为胆盐和脂肪酶的吸附提供了空间障碍。因此,吐温 80 显著地延迟了脂质消化。卵磷脂的引入逐渐取代界面上的吐温 80 分子,从而为胆盐和脂肪酶的吸附提供了空间。此外,随着卵磷脂浓度与吐温 80 浓度之比的增加,卵磷脂逐渐成为界面性质的主导因素。因此,脂质消化的速率加快。因此,通过复合不同比例的卵磷脂和吐温 80,可以得到一系列具有不同脂质消化速率的乳液。这项研究为根据特定需求合理设计食品乳液提供了依据。

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