School of Pharmacy, College of Health and Medical Sciences, Haramaya University, P. O. Box 235, Harar, Ethiopia.
School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Sci Rep. 2024 Aug 1;14(1):17751. doi: 10.1038/s41598-024-67688-1.
Access to antibiotic medications is critical to achieving the Sustainable Development Goal for good health and well-being. However, non-prescribed and informal sources are implicated as the most common causes of inappropriate antibiotic access practices, resulting in untargeted therapy, which leads to antibiotic resistance. Hence, knowing antibiotic access practices at the community level is essential to target misuse sources. In this study, 2256 household representatives were surveyed between July and September 2023 to examine their antibiotic access practices. Of 1245 household members who received antibiotics, 45.6% did so inappropriately. Non-prescribed antibiotic access was more common among urban residents and individuals not enrolled in health insurance schemes. This means of antibiotic access was also more common among individuals concerned about distance, drug availability, and healthcare convenience at public facilities. In addition, women and rural individuals were more likely to get antibiotics from unauthorized sources. Unrestricted antibiotic dispensing practices in urban areas enabled their non-prescribed access, while unlicensed providers prevailed with this access practice in rural areas. In this regard, personal behaviors and healthcare-related gaps such as the lack of health insurance, inconvenience, and drug unavailability have led community members to seek antibiotics from unofficial and non-prescribed sources. Targeting the identified behavioral and institutional factors can enhance antibiotic access through prescriptions, hence reducing antibiotic resistance.
获得抗生素药物对于实现良好健康和福祉的可持续发展目标至关重要。然而,非处方和非正式渠道被认为是导致抗生素获取不当的最常见原因,导致无针对性治疗,进而导致抗生素耐药性。因此,了解社区层面的抗生素获取实践对于针对滥用来源至关重要。在这项研究中,2023 年 7 月至 9 月期间对 2256 户家庭代表进行了调查,以调查他们的抗生素获取实践。在 1245 名接受抗生素的家庭成员中,45.6%的人使用不当。城市居民和未参加医疗保险计划的个人更有可能通过非处方途径获得抗生素。这种获取抗生素的方式在关注距离、药物可用性和公共设施医疗便利性的人群中更为常见。此外,女性和农村居民更有可能从未经授权的来源获得抗生素。城市地区不受限制的抗生素配给做法使其能够进行非处方获取,而农村地区则是无照提供者主导这种获取方式。在这方面,个人行为和与医疗相关的差距,如缺乏医疗保险、不便和药物短缺,导致社区成员从非官方和非处方渠道寻求抗生素。针对确定的行为和制度因素,可以通过处方增强抗生素获取,从而减少抗生素耐药性。