From the Departments of Nuclear Medicine.
Internal Medicine.
Clin Nucl Med. 2024 Sep 1;49(9):e482-e483. doi: 10.1097/RLU.0000000000005345. Epub 2024 Jul 31.
Relapsing polychondritis (RP) is an uncommon autoimmune disease that causes inflammation of the cartilage and proteoglycan-rich structures, including the ear, nose, and airway. Paraneoplastic RP is a subset of RP that occurs in some individuals following the detection and treatment of certain types of cancers. FDG PET/CT helps with early diagnosis of RP, identifying inflammatory areas even in the absence of symptoms, and guiding the selection of appropriate biopsy sites. Here, we present a case of adenocarcinoma of the lung presenting with paraneoplastic symptoms of RP as initial presentation, and symptoms were resolved after 3 cycles of chemotherapy.
复发性多软骨炎(RP)是一种罕见的自身免疫性疾病,可引起软骨和富含蛋白聚糖的结构炎症,包括耳朵、鼻子和气道。副肿瘤性 RP 是 RP 的一个亚组,在某些人在检测和治疗某些类型的癌症后发生。FDG PET/CT 有助于 RP 的早期诊断,即使在没有症状的情况下也能识别炎症区域,并指导选择合适的活检部位。在这里,我们介绍了一例以副肿瘤性 RP 症状为首发表现的肺癌腺癌病例,经 3 个周期化疗后症状缓解。