University Malaya Medical Center, University Malaya, Division of Respiratory Medicine, Department of Medicine, Lembah Pantai, Kuala Lumpur, Malaysia.
Queen Elizabeth Hospital, Respiratory Department, Jalan Penampang, Kota Kinabalu, Sabah, Malaysia.
Med J Malaysia. 2024 Jul;79(4):490-493.
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is commonly used to diagnose and stage lung cancer. In clinical practice, cytology specimens from EBUS-TBNA may be low in cellularity, especially with necrotic lesions. Endobronchial ultrasound-guided transbronchial mediastinal cryobiopsy (EBUS-TBMC) has recently become the preferred method for obtaining histology biopsy. This retrospective cohort study analysed the first 30 patients who have undergone EBUS-TBMC in a tertiary centre in Malaysia. EBUS-TBMC demonstrated a high diagnostic yield and good safety profile. All the samples obtained were adequate for the detection of driver alteration by next-generation sequencing.
经支气管超声引导针吸活检术（EBUS-TBNA）常用于诊断和分期肺癌。在临床实践中，EBUS-TBNA 的细胞学标本可能细胞数量较少，尤其是伴有坏死病变时。经支气管超声引导针吸纵隔活检术（EBUS-TBMC）最近已成为获取组织学活检的首选方法。本回顾性队列研究分析了马来西亚一家三级中心的前 30 例接受 EBUS-TBMC 的患者。EBUS-TBMC 显示出较高的诊断率和良好的安全性。所有获得的样本均足以通过下一代测序检测驱动基因突变。
