Mponda John Samson, Muula Adamson Sinjani, Choko Augustine, Ajuwon Ademola Johnson, Moody Jones Olanrewaju
Department of Pharmacognosy, Faculty of Pharmacy, University of Ibadan, Nigeria.
Africa Centre of Excellence in Public Health and Herbal Medicine, Kamuzu University of Health Sciences, Malawi.
Malawi Med J. 2024 Mar 20;36(1):13-22. doi: 10.4314/mmj.v36i1.3. eCollection 2024 Mar.
Consumption of herbal medicines among people living with HIV is a common practice in Sub-Saharan Africa. The utilization of herbal medicines was at 17.5% and 67.9% in Malawi and Nigeria, respectively. There is inadequate data on use and adverse reactions (ADRs) reporting of herbal medicines among people living with HIV (PLWHIV). This study was designed to investigate use and ADRs reporting of herbal medicines among PLWHIV at the University Teaching Hospitals in Blantyre, Malawi and Ibadan, Nigeria.
A cross-sectional study was conducted among PLWHIV attending Antiretroviral Therapy (ART) clinic at Queen Elizabeth Central Hospital, Blantyre, Malawi and University College Hospital, Ibadan, Nigeria. A structured questionnaire was administered to 360 and 370 participants in Blantyre and Ibadan respectively, through face-to-face interviews after obtaining their informed consent.
The prevalence of herbal medicines use among PLWHIV in Malawi and Nigeria was at 80.6% and 55.7% (p<0.001), respectively. The most frequently used herbal medicines in Malawi were (14.0%), (14.0%), (13.0%) and (7.0%). Likewise, in Nigeria, the most commonly used herbal medicines were (15.0%), (14.0%), (9.0%), and (11.0%). The major reason for herbal medicines' use in Malawi was ready availability (42.1%) and perception that it boosts immunity (44.6%) in Nigeria. The PLWHIV reported experiencing suspected herbal medicine ADRs in Malawi (3.9%) and in Nigeria (8.0%).
A higher percentage of people living with HIV are using herbal medicines in Malawi as well as in Nigeria. In both countries, a few participants reported experiencing suspected ADRs related to herbal medicines.
在撒哈拉以南非洲地区,感染艾滋病毒的人群中使用草药是一种常见做法。在马拉维和尼日利亚,草药的使用率分别为17.5%和67.9%。关于感染艾滋病毒人群(PLWHIV)使用草药及不良反应(ADR)报告的数据不足。本研究旨在调查马拉维布兰太尔市和尼日利亚伊巴丹市大学教学医院中PLWHIV使用草药及ADR报告情况。
对在马拉维布兰太尔市伊丽莎白女王中央医院和尼日利亚伊巴丹市大学学院医院接受抗逆转录病毒治疗(ART)门诊的PLWHIV进行了一项横断面研究。在获得他们的知情同意后,通过面对面访谈分别向布兰太尔市的360名和伊巴丹市的370名参与者发放了一份结构化问卷。
马拉维和尼日利亚的PLWHIV中使用草药的患病率分别为80.6%和55.7%(p<0.001)。在马拉维,最常用的草药是[草药名称1](14.0%)、[草药名称2](14.0%)、[草药名称3](13.0%)和[草药名称4](7.0%)。同样,在尼日利亚,最常用的草药是[草药名称5](15.0%)、[草药名称6](14.0%)、[草药名称7](9.0%)和[草药名称8](11.0%)。在马拉维,使用草药的主要原因是容易获得(42.1%),在尼日利亚是认为其能增强免疫力(44.6%)。PLWHIV报告在马拉维有3.9%、在尼日利亚有8.0%经历过疑似草药ADR。
在马拉维和尼日利亚,使用草药的艾滋病毒感染者比例更高。在这两个国家,少数参与者报告经历过与草药相关的疑似ADR。