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肿瘤性急性冠状动脉综合征一例——病例报告及文献综述

A Case of Tumoral Acute Coronary Syndrome - Case Report and Literature Review.

作者信息

Carvalho Catarina Isabel Ribeiro, Carvalho Pedro Miguel Rocha, Silveira Maria Inês Costa, Baptista Ana Isabel Santos

机构信息

Department of Cardiology, Trás-os-Montes e Alto Douro Hospital Centre, Vila Real, Portugal.

出版信息

J Cardiovasc Echogr. 2024 Apr-Jun;34(2):93-95. doi: 10.4103/jcecho.jcecho_69_23. Epub 2024 Jun 28.

Abstract

Cardiovascular disease and cancer constitute the most prevalent illnesses worldwide. Cancer patients show an increased risk of coronary artery disease not only due to shared cardiovascular risk factors, a pro-inflammatory and prothrombotic state induced by cancer itself, the cardiovascular toxicity of cancer therapy, or rarely, due to extrinsic compression of a coronary artery by the primary tumor or a metastatic lesion. Here, we present the case of a 59-year-old man with squamous cell carcinoma of the lung presented with asymptomatic diffuse ST segment depression and troponin T increase. Echocardiography revealed a large mass adjacent to the right atrium, atrioventricular groove, and basal segment of the anterior wall of the left ventricle, which the computed tomography scan showed to encase and probably compress the anterior descending coronary artery. Thus, the patient was diagnosed with acute coronary syndrome due to anterior descendent coronary artery compression by a neoplastic lung mass.

摘要

心血管疾病和癌症是全球最常见的疾病。癌症患者患冠状动脉疾病的风险增加,这不仅是由于共同的心血管危险因素、癌症本身引发的促炎和促血栓状态、癌症治疗的心血管毒性,或者很少见的情况,即原发性肿瘤或转移病灶对冠状动脉的外在压迫。在此,我们报告一例59岁男性肺鳞状细胞癌患者,其表现为无症状的弥漫性ST段压低和肌钙蛋白T升高。超声心动图显示右心房、房室沟和左心室前壁基底段附近有一个大肿块,计算机断层扫描显示该肿块包裹并可能压迫前降支冠状动脉。因此,该患者被诊断为因肺部肿瘤压迫前降支冠状动脉导致的急性冠状动脉综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d3c/11288299/885e89a7720a/JCE-34-93-g001.jpg

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