Cadeddu Dessalvi Christian, Deidda Martino, Giorgi Mauro, Colonna Paolo
Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Department of Cardiology, University Hospital Città della Scienza e Salute, Molinette Hospital, Turin, Italy.
J Cardiovasc Echogr. 2020 Apr;30(Suppl 1):S11-S16. doi: 10.4103/jcecho.jcecho_3_19. Epub 2020 Apr 10.
Cardiovascular complications during chemotherapy and radiotherapy are becoming an increasing problem because many patients with cancer are treated with agents that exert significant vascular toxicity. Coronary heart disease in patients with cancer presents particular challenges, which directly impact the management of both the coronary disease and malignancy. Several chemotherapeutic agents have been shown to trigger ischemic heart disease, and as it has happened for myocardial cardiotoxicity, more attention should be dedicated to improving early recognition and prevention of cardiac vascular toxicity. Cardiac imaging could facilitate early detection of vascular toxicity, but a thorough risk stratification should always be performed to identify patients at higher risk of vascular impairment.
化疗和放疗期间的心血管并发症正成为一个日益严重的问题，因为许多癌症患者接受的治疗药物具有显著的血管毒性。癌症患者的冠心病带来了特殊挑战，这直接影响到冠心病和恶性肿瘤的治疗。几种化疗药物已被证明会引发缺血性心脏病，就像心肌心脏毒性一样，应更加关注改善心脏血管毒性的早期识别和预防。心脏成像有助于早期发现血管毒性，但应始终进行全面的风险分层，以识别血管损伤风险较高的患者。
