Buil Jochem B, Meijer Eelco F J, den Reijer Martijn, Zeeuwen-Franssen Manon E J, Melchers Willem J G, Verweij Paul E
Radboudumc, afd. Medische Microbiologie, Nijmegen.
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Ned Tijdschr Geneeskd. 2024 Jul 23;168:D7945.
is a recently identified dermatophyte that frequently causes extensive and persistent dermatomycosis, particularly tinea corporis, tinea cruris, and tinea faciei. The infection is frequently encountered in countries of the Indian subcontinent and surrounding areas. In Europe, has mainly been detected in patients with an epidemiological link to the aforementioned regions. Unlike dermatomycoses caused by other dermatophyte species, infections caused by often exhibit treatment failure with commonly prescribed antifungal drugs. Reduced susceptibility to terbinafine is often observed in . In addition, reduced susceptibility to itraconazole has also been reported. Due to the extensive and persistent nature of the infection, as well as the reduced susceptibility to antifungal drugs, international experts recommend aggressive treatment of using a combination of oral and topical antifungals. Susceptibility testing may be warranted to guide treatment decisions. Early recognition of infections is crucial to prevent prolonged recurrences.
是一种最近被鉴定出的皮肤癣菌，常引起广泛且持续的皮肤真菌病，尤其是体癣、股癣和面癣。在印度次大陆及周边地区的国家，这种感染很常见。在欧洲，主要在与上述地区有流行病学关联的患者中检测到。与其他皮肤癣菌引起的皮肤真菌病不同，由该菌引起的感染通常对常用的抗真菌药物治疗无效。在该菌中常观察到对特比萘芬的敏感性降低。此外，也有报道称对伊曲康唑的敏感性降低。由于感染具有广泛性和持续性，以及对抗真菌药物的敏感性降低，国际专家建议使用口服和外用抗真菌药物联合积极治疗该菌感染。可能需要进行药敏试验以指导治疗决策。早期识别该菌感染对于防止长期复发至关重要。
