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[在评估宫颈癌区域淋巴结功能活性中白细胞的干扰素形成特性]

[Interferon-forming properties of the leukocytes in assessing the functional activity of the regional lymph nodes in cervical cancer].

作者信息

Vorontsova A L, Vinnitskaia V K, Balitskiĭ K P, Ligirda F D

出版信息

Vopr Onkol. 1979;25(11):44-7.

PMID:390875
Abstract

In the present work the authors have employed their personal modification of the technic of interferon reaction of lymphocytes, which consists in using the lymphocytes isolated from regional lymph nodes but not from the peripheral blood as described in the literature. The titres of interferon produced in vitro by the lymphocytes of lymph nodes, removed during the operation in cervical cancer patients, were shown to correlate well with the clinico-morphological changes, indicating the rate of the regional lymphoid tissue response. The mentioned correlation speaks in favour of the prognostic value of the interferon reaction of regional lymph nodes lymphocytes in cervical cancer.

摘要

在本研究中,作者采用了他们个人改良的淋巴细胞干扰素反应技术,该技术的不同之处在于使用从区域淋巴结而非如文献所述从外周血中分离出的淋巴细胞。结果显示,在宫颈癌患者手术过程中切除的淋巴结淋巴细胞体外产生的干扰素效价与临床形态学变化密切相关,这表明了区域淋巴组织反应的速率。上述相关性支持了区域淋巴结淋巴细胞干扰素反应在宫颈癌中的预后价值。

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