Quastel J H
Mol Cell Biochem. 1985 Nov;69(1):17-26. doi: 10.1007/BF00225923.
This lecture consists of a short appraisal of some of the main features that have characterized the growth of biochemistry during the course of the 20th century. It dwells on the early impacts of vitalism, the emergence and elucidation of the vitamins, the discovery of coenzymes, the concept of active centres of enzymes, the development of experimental techniques (including the use of isotopes), the genetic code, and on the development of molecular biology and closely allied fields of investigation. It concludes with a consideration of the influence of the study of membranes and of neurochemistry on current biochemical thought.
本次讲座简要评估了20世纪生物化学发展过程中的一些主要特征。它详述了活力论的早期影响、维生素的出现与阐明、辅酶的发现、酶活性中心的概念、实验技术（包括同位素的应用）的发展、遗传密码，以及分子生物学和紧密相关研究领域的发展。讲座最后探讨了膜研究和神经化学对当前生化思想的影响。
