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[淋巴造影、计算机断层扫描及超声在儿童膈下恶性淋巴瘤诊断中的价值]

[Value of lymphography, computer tomography and ultrasound in the diagnosis of infradiaphragmatic malignant lymphomas in children].

作者信息

Winkler P, Amon O, Bohndorf K

出版信息

Monatsschr Kinderheilkd. 1985 Nov;133(11):823-7.

PMID:3908916
Abstract

25 children with Hodgkin's disease and 6 children with Non-Hodgkin-lymphoma were reviewed in order to compare the diagnostic value of lymphography, CT and sonography. As compared with staging-laparotomy, sensitivity for the detection of lymph node involvement was 78% for lymphography, 33% for CT and 57% for the ultrasound examination. Specifity was 55%, 88%, and 83% respectively. Undetected involvement of splenic and liver hilar lymph nodes, unspecific lymphadenitis and fluid-filled bowl loops caused most of the false negative and false positive findings. In 10 children histological examination showed splenic involvement. No splenic lesion was seen by CT in 7 of these children. Splenic disease could be clearly identified by ultrasound in only one child. Although children with lymph node involvement had always splenic manifestations of malignant lymphomatous disease it is concluded that staging laparotomy is an indispensable tool in diagnosing malignant lymphoma. Lymphography should not be abandoned with children. It should be used in combination with either CT or ultrasound examination.

摘要

对25例霍奇金病患儿和6例非霍奇金淋巴瘤患儿进行了回顾性研究,以比较淋巴造影、CT和超声检查的诊断价值。与分期剖腹术相比,淋巴造影检测淋巴结受累的敏感性为78%,CT为33%,超声检查为57%。特异性分别为55%、88%和83%。脾和肝门淋巴结未被检测到的受累、非特异性淋巴结炎和充满液体的肠袢导致了大多数假阴性和假阳性结果。10例患儿的组织学检查显示有脾受累。其中7例患儿CT未发现脾病变。超声仅在1例患儿中能清晰识别脾疾病。尽管有淋巴结受累的患儿总是有恶性淋巴瘤疾病的脾表现,但得出的结论是分期剖腹术是诊断恶性淋巴瘤必不可少的工具。对于儿童不应放弃淋巴造影。它应与CT或超声检查联合使用。

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