Poulsen Tobias Malthe, Pilgaard Mads Lund, Lund Lars
Department of Urology, Odense University Hospital, J.B.Winsløwsvej 4, 5000, Odense, Denmark.
Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Int Urol Nephrol. 2025 Jan;57(1):1-7. doi: 10.1007/s11255-024-04163-w. Epub 2024 Aug 1.
Megaureter (MU) is an uncommon condition in adults. The aim is to present a review of the current literature.
A literature search was conducted to explore the current literature including case reports on MU in adults in the period 2003-2023. Each case was characterised in terms of the eight categories: sex, age, etiology, location, symptoms, diagnostic tool used, type of treatment and follow-up.
There was no meta-analysis but two reviews. Total, 39 case reports were included based on 35 articles. The most common observations for the first four categories were male (sex), age below 40 (age), obstructed MU (etiology) and left-sided MU (location). Almost every patient appeared with symptoms, most frequently flank pain, abdominal pain and recurrent urinary tract infections. CT scan and transabdominal ultrasonography are the most commonly used diagnostic tools. Most cases underwent either laparoscopic or open surgical treatment with ureteral reimplantation as the most performed surgical procedure. A majority of the patients had an uneventful follow-up.
MU in adults is a rare condition presenting with heterogeneous symptoms. CT scan and transabdominal ultrasonography should be used as diagnostic tools. Nearly all patients underwent surgical treatment with an uneventful follow-up. Complications such as stone formation and altered function of the affected kidney are common. Surgical treatment is recommended and is determined by consideration of age, symptoms, ureteral extension and progressive loss of renal function.
