Nichols Paige, Esposito Adrienne, Kolojeski Maria, Keomany Jennifer, Okut Hayrettin, Morgan Jacqueline, Miller Kevin
University of Kansas School of Medicine-Wichita, Wichita, KS.
Department of Obstetrics and Gynecology.
Kans J Med. 2024 Jul 24;17(4):74-77. doi: 10.17161/kjm.vol17.21651. eCollection 2024.
Vaginal cuff dehiscence (CD) after hysterectomy is a rare but serious complication of robotic-assisted laparoscopic total hysterectomy (RLTH). The authors of this study aimed to compare the incidence and risk factors of CD following RLTH among patients with and without endometrial cancer.
This retrospective study included women aged 18 years or older who underwent RLTH by two surgeons at a single institution from 2013 to 2018. Patients with conversion to laparotomy, recent chemotherapy or radiation, or non-uterine malignancy were excluded. Data were abstracted from medical records.
Of 950 patients meeting inclusion criteria, 50.7% had endometrial cancer. CD was reported in 2.5% of all patients. While adjusting for cancer status, age, sexual activity after surgery, distance from home to location of surgery, and time interval from surgery to loss to followup, obese patients were 25.1% less likely than non-obese patients to experience CD (62.5 vs. 37.5, p = 0.01). Surgeon A had a 2.8 times higher CD rate than surgeon B (70.8 vs. 29.2, p = 0.03). No other factors predicted CD.
Endometrial cancer patients were not at greater risk of experiencing CD compared to non-cancer patients. Surgeon differences and body mass index (BMI) were associated with CD risk, with normal BMI patients at higher risk.
子宫切除术后阴道残端裂开(CD)是机器人辅助腹腔镜全子宫切除术(RLTH)一种罕见但严重的并发症。本研究的作者旨在比较子宫内膜癌患者和非子宫内膜癌患者RLTH术后CD的发生率及危险因素。
这项回顾性研究纳入了2013年至2018年在单一机构由两位外科医生进行RLTH的18岁及以上女性。排除中转开腹、近期接受化疗或放疗或患有非子宫恶性肿瘤的患者。数据从病历中提取。
在950例符合纳入标准的患者中,50.7%患有子宫内膜癌。所有患者中2.5%报告发生了CD。在对癌症状态、年龄、术后性活动、家到手术地点的距离以及手术至失访的时间间隔进行调整后,肥胖患者发生CD的可能性比非肥胖患者低25.1%(62.5对37.5,p = 0.01)。外科医生A的CD发生率比外科医生B高2.8倍(70.8对29.2,p = 0.03)。没有其他因素可预测CD。
与非癌症患者相比,子宫内膜癌患者发生CD的风险并不更高。外科医生差异和体重指数(BMI)与CD风险相关,BMI正常的患者风险更高。